About: Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)
Creator	Sugiyama, K Hatakeyama, K Kasai, H Kasai, M Kato, S
Source	Medline; PMC
abstract	The acetylesterase (AE) activity of DVIM (diarrhea virus of infant mice) was assigned to the haemagglutinin-esterase (HE) protein. The substrate specificity was examined using the natural substrate bovine submaxillary mucin (BSM) and/or synthetic substrates p-nitrophenylacetate (p-NiA) and α-naphthylacetate (α-NA) and compared with several strains of MHV and influenza viruses. The AE of DVIM hydrolyzed the O-acetylester bond of BSM, and the two synthetic substrates p-NiA and α-NA in vitro. MHV-S reacted efficiently with both p-NiA and α-NA but less with BSM. Influenza virus (C/Miyagi/77) reacted with BSM efficiently, however reacted with p-NiA weakly, but not with α-NA at all. Thus, the AE-reactivity of DVIM was distinctly different from that of MHV-S and influenza C virus, suggesting that the AE of HE may have a modified function. Isolation of HE by the treatment with non ionic detergent NP40, resulted in globules approximately 5 nm in diameter. DVIM-binding proteins were demonstrated in the plasma membrane of mouse intestinal brush-border cells and hepatocytes. The same protein was recognized by MHV-S and MHV-4. The cell membranes obtained from these target tissues were substrates for the AE of DVIM. The biological importance of the HE protein for DVIM is discussed.
has issue date	2014-04-07(xsd:dateTime)
bibo:doi	10.1007/s007050050395
bibo:pmid	9739331
has license	no-cc
sha1sum (hex)	9aeada9f8181ee2edb3301898299a4241765a1a4
schema:url	https://doi.org/10.1007/s007050050395
resource representing a document's title	Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)
has PubMed Central identifier	PMC7086961
has PubMed identifier	9739331
schema:publication	Arch Virol
resource representing a document's body	covid:9aeada9f8181ee2edb3301898299a4241765a1a4#body_text
is schema:about of	named entity 'protein' named entity 'plasma membrane' named entity 'mucin' named entity 'diarrhea' named entity 'MHV' named entity 'The' named entity 'The' covid:arg/9aeada9f8181ee2edb3301898299a4241765a1a4 named entity 'bond' named entity 'substrates' named entity 'substrates' named entity 'The cell' named entity 'cells' named entity 'infant' named entity '5 nm' named entity 'substrate specificity' named entity 'bovine' named entity 'influenza' named entity 'substrates' named entity 'substrates' named entity 'influenza C virus' named entity 'haemagglutinin' named entity 'influenza viruses' named entity 'detergent' named entity 'plasma membrane' named entity 'murine' named entity 'Haemagglutinin' named entity 'esterase' named entity 'substrates' named entity 'modified' named entity 'virus' named entity 'activity assays' named entity 'polyacrylamide' named entity 'protein' named entity 'mice' named entity 'clones' named entity 'MHV' named entity 'hepatocytes' named entity 'protein' named entity 'acetate' named entity 'glycine' named entity 'protein labeling' named entity 'Hydrolysis' named entity 'methionine' named entity 'MHV' named entity 'enzymatic activity' named entity 'biotinylated' named entity 'reducing conditions' named entity 'plasma membranes' named entity 'Coronaviruses' named entity 'liver' named entity 'MHV' named entity 'Viral protein' named entity 'sialylated' named entity 'reducing conditions' named entity 'acetylesterase' named entity 'myeloma' named entity 'MHV' named entity 'acetate' named entity 'sialoglycoconjugates' named entity 'liver' named entity 'PBS' named entity 'dimeric' named entity 'virus' named entity 'PBS' named entity 'ethanol' named entity 'protein' named entity 'protein' named entity 'substrate' named entity 'Freund's adjuvant' named entity 'Murine coronavirus' named entity 'membrane proteins' named entity 'negative staining' named entity 'microtiter plates' named entity 'titer' named entity 'isotypes' named entity 'mice'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software