About: Pregnancy and postpartum outcomes in a universally tested population for SARS‐CoV‐2 in New York City: A prospective cohort study

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About: Pregnancy and postpartum outcomes in a universally tested population for SARS‐CoV‐2 in New York City: A prospective cohort study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Pregnancy and postpartum outcomes in a universally tested population for SARS‐CoV‐2 in New York City: A prospective cohort study
Creator	Zhao, Zhen Baergen, Rebecca Kubiak, Jeffrey Prabhu, Malavika Riley, Laura Singh, Harjot Snyder, Jon Dipace, Jennifer Cagino, Kristen Friedlander, Rachel Glynn, Shannon Kalish, Robin Matthews, Kathy Oxford, Corrina Razavi, Armin Skupski, Daniel Yang, Yawei
source	Medline; PMC
abstract	OBJECTIVE: To describe differences in outcomes between pregnant women with and without COVID‐19 DESIGN: Prospective cohort study of pregnant women consecutively admitted for delivery, and universally tested via nasopharyngeal (NP) swab for SARS‐CoV‐2 using reverse transcriptase polymerase chain reaction (RT‐PCR). All infants of mothers with COVID‐19 underwent SARS‐CoV‐2 testing. SETTING: Three New York City hospitals POPULATION: Pregnant women > 20 weeks’ gestation admitted for delivery METHODS: Data were stratified by SARS‐CoV‐2 result and symptomatic status, and summarized using parametric and nonparametric tests. MAIN OUTCOME MEASURES: Prevalence and outcomes of maternal COVID‐19; obstetric outcomes; neonatal SARS‐CoV‐2; placental pathology. RESULTS: Of 675 women admitted for delivery, 10.4% were positive for SARS‐CoV‐2, of whom 78.6% were asymptomatic. We observed differences in sociodemographics and comorbidities between women with symptomatic vs. asymptomatic vs. no COVID‐19. Cesarean delivery rates were 46.7% in symptomatic COVID‐19, 45.5% in asymptomatic COVID‐19, and 30.9% without COVID‐19 (p=0.044). Postpartum complications (fever, hypoxia, readmission) occurred in 12.9% of women with COVID‐19 vs 4.5% of women without COVID‐19 (p<0.001). No woman required mechanical ventilation, and no maternal deaths occurred. Among 71 infants tested, none were positive for SARS‐CoV‐2. Placental pathology demonstrated increased frequency of fetal vascular malperfusion, indicative of thrombi in fetal vessels, in women with vs. without COVID‐19 (48.3% vs 11.3%, p <0.001). CONCLUSION: Among pregnant women with COVID‐19 at delivery, we observed increased cesarean delivery rates and increased frequency of maternal complications in the postpartum period. Additionally, intraplacental thrombi may have maternal and fetal implications for COVID‐19 infections remote from delivery.
has issue date	2020-07-07(xsd:dateTime)
bibo:doi	10.1111/1471-0528.16403
bibo:pmid	32633022
has license	no-cc
sha1sum (hex)	9b29d489c1d7c4db97da2d6759986e958a4d556d
schema:url	https://doi.org/10.1111/1471-0528.16403
resource representing a document's title	Pregnancy and postpartum outcomes in a universally tested population for SARS‐CoV‐2 in New York City: A prospective cohort study
has PubMed Central identifier	PMC7361728
has PubMed identifier	32633022
schema:publication	BJOG
resource representing a document's body	covid:9b29d489c1d7c4db97da2d6759986e958a4d556d#body_text
is schema:about of	named entity 'chain reaction' named entity 'COVID' named entity 'New York City' named entity 'SARS' named entity 'asymptomatic' named entity 'SARS-CoV-2' named entity 'postpartum period' named entity 'respiratory support' named entity 'gestation' named entity 'histologically' named entity 'cesarean delivery' named entity 'control group' named entity 'neonatal' named entity 'intrauterine infections' named entity 'asymptomatic' named entity 'COVID' named entity 'sore throat' named entity 'oxygen supplementation' named entity 'prospective cohort study' named entity 'COVID' named entity 'physiologic response' named entity 'postpartum' named entity 'prematurity' named entity 'neonates' named entity 'neonatal' named entity 'COVID' named entity 'neonatal' named entity 'fetal' named entity 'COVID' named entity 'hypoxia' named entity 'stillbirths' named entity 'cough' named entity 'postpartum' named entity 'villi' named entity 'meconium' named entity 'SARS-CoV-2' named entity 'COVID' named entity 'follow-up' named entity 'chest imaging' named entity 'COVID' named entity 'pathologist' named entity 'hypoxia' named entity 'chronic hypertension' named entity 'COVID' named entity 'vaginal delivery' named entity 'institutional review board' named entity 'cesarean delivery' named entity 'venous thromboembolic disease' named entity 'COVID' named entity 'preterm birth' named entity 'COVID' named entity 'neonate' named entity 'COVID' named entity 'neonatal intensive care unit' named entity 'COVID-19' named entity 'postpartum' named entity 'COVID' named entity 'multifocal pneumonia' named entity 'staining' named entity 'asymptomatic' named entity 'fever' named entity 'cesarean delivery' named entity 'placental' named entity 'comorbidities' named entity 'gestation'

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