About: Correlation of High-Resolution CT, Symptoms, and Pulmonary Function in Patients During Recovery From Severe Acute Respiratory Syndrome

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About: Correlation of High-Resolution CT, Symptoms, and Pulmonary Function in Patients During Recovery From Severe Acute Respiratory Syndrome Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Correlation of High-Resolution CT, Symptoms, and Pulmonary Function in Patients During Recovery From Severe Acute Respiratory Syndrome
Creator	Chen, Cheng-Yu Chang, Wei-Chou Hsu, Hsian-He Tsai, Chen-Liang Tung, Ho-Jui Tzao, Ching Wu, Chin-Pyng
source	Elsevier; Medline; PMC
abstract	Study objectives: Little is known of the nature of the recovery period after severe acute respiratory syndrome (SARS) infection. We hypothesized that structural changes of the lung might correlate with symptoms and pulmonary function. To answer this question, we correlate findings of high-resolution CT (HRCT) with dyspnea scores and results of pulmonary function tests in patients during recovery from SARS. Design: Retrospective follow-up cohort study. Setting: University hospital. Patients: Nineteen patients who recovered from SARS-related hospitalization. Measurements: The study included HRCT scores (0 to 100), dyspnea scores (1 to 4), static and dynamic lung volumes, and diffusing capacity of the lung for carbon monoxide (Dlco). Results: The interval between hospital discharge and HRCT study or functional assessment was 31.2 ± 4.8 days (range, 25 to 38 days) [mean ± SD]. All patients had HRCT abnormalities and were assigned to two groups: ground-glass opacity (GGO) only (n = 7, 36.8%) and GGO with fibrosis (GGO+F) [n = 12, 63.2%]. Most patients (16 of 19, 84.2%) had no zonal predominance. HRCT scores correlated well with dyspnea scores (r = 0.78, p < 0.01) and with a variety of pulmonary functional variables, with Dlco being the most significant (r = − 0.923, p < 0.001). Compared with the GGO group, the GGO+F group showed significantly lower FEV1, FVC, total lung capacity, residual volume, and Dlco. Conclusions: HRCT findings correlate well with functional studies and clinical symptoms during recovery from SARS. Longer-term follow-up studies in a larger cohort of patients should be performed to investigate the clinical outcome of recovered SARS patients.
has issue date	2004-07-31(xsd:dateTime)
bibo:doi	10.1378/chest.126.1.149
bibo:pmid	15249456
has license	els-covid
sha1sum (hex)	9b2b2560c7372956ac851ab78c8a72cc5dde24d7
schema:url	https://doi.org/10.1378/chest.126.1.149
resource representing a document's title	Correlation of High-Resolution CT, Symptoms, and Pulmonary Function in Patients During Recovery From Severe Acute Respiratory Syndrome
has PubMed Central identifier	PMC7094423
has PubMed identifier	15249456
schema:publication	Chest
resource representing a document's body	covid:9b2b2560c7372956ac851ab78c8a72cc5dde24d7#body_text
is schema:about of	named entity 'PATIENTS' named entity 'DLCO' named entity 'Patients' named entity 'hypothesized' named entity 'hospital' named entity 'ground-glass opacity' named entity 'PATIENTS' named entity 'COHORT STUDY' named entity 'MEASUREMENTS' named entity 'RELATED' named entity 'COMPARED' named entity 'GROUP' named entity 'FUNCTIONAL ASSESSMENT' named entity '158' named entity 'SCORES' named entity 'LUNG' named entity 'STRUCTURAL' named entity 'LARGER' named entity 'ABNORMALITIES' named entity 'PULMONARY FUNCTION TESTS' named entity 'TOTAL LUNG CAPACITY' named entity 'RESULTS' named entity 'SARS' named entity 'ASSIGNED' named entity 'RECOVERED' named entity 'SYMPTOMS' named entity 'OUTCOME' named entity 'DYSPNEA' named entity 'STATIC' named entity 'RECOVERY' named entity 'VARIABLES' named entity 'HIGH-RESOLUTION CT' named entity 'FIBROSIS' named entity 'COHORT' named entity 'RESIDUAL VOLUME' named entity 'PULMONARY FUNCTION' named entity 'RECOVERY' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'CORRELATION' named entity 'HIGH-RESOLUTION CT' named entity 'INTERVAL' named entity 'FOLLOW-UP STUDIES' named entity 'DESIGN' named entity 'PULMONARY FUNCTION' named entity 'OBJECTIVES' named entity 'HRCT' named entity 'FOLLOW-UP' named entity '0.78' named entity 'CLINICAL' named entity 'HOSPITALIZATION' named entity 'KNOWN' named entity 'LUNG VOLUMES' named entity 'HOSPITAL DISCHARGE' named entity 'PULMONARY' named entity '923' named entity 'INFECTION' named entity '80%' named entity '100%' named entity '0.01' named entity 'SYMPTOMS' named entity 'NINETEEN' named entity 'NATURE' named entity 'DYNAMIC' named entity 'CONCLUSIONS' named entity 'BEING' named entity 'SETTING' named entity 'CLINICAL SYMPTOMS' named entity 'UNIVERSITY HOSPITAL' named entity 'RETROSPECTIVE' named entity 'TO INVESTIGATE' named entity 'DLCO' named entity 'FVC' named entity 'MOST SIGNIFICANT' named entity 'STUDY' named entity '0.001'

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