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About:
Histopathological findings in fatal COVID-19 severe acute respiratory syndrome: preliminary experience from a series of 10 Spanish patients
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An Entity of Type :
schema:ScholarlyArticle
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wasabi.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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Attributes
Values
type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Histopathological findings in fatal COVID-19 severe acute respiratory syndrome: preliminary experience from a series of 10 Spanish patients
Creator
Luis, Jose
Argueta, Alan
Carmona Torre, Francisco
De Andrea, Carlos
Echarri, Gema
Ezponda, Ana
Fernández, Mirian
García-Tobar, Laura
Iborra, Carlota
Landecho, Manuel
Lozano, Maria
Pozo, Del
Quiroga, Jorge
Recalde, Borja
Zulueta, Javier
source
Medline; PMC
abstract
In December 2019, an outbreak of severe acute respiratory syndrome associated to SARS-CoV2 was reported in Wuhan, China. To date, little is known on histopathological findings in patients infected with the new SARS-CoV2. Lung histopathology shows features of acute and organising diffuse alveolar damage. Subtle cellular inflammatory infiltrate has been found in line with the cytokine storm theory. Medium-size vessel thrombi were frequent, but capillary thrombi were not present. Despite the elevation of biochemical markers of cardiac injury, little histopathological damage could be confirmed. Viral RNA from paraffin sections was detected at least in one organ in 90% patients.
has issue date
2020-08-23
(
xsd:dateTime
)
bibo:doi
10.1136/thoraxjnl-2020-215577
bibo:pmid
32839288
has license
no-cc
sha1sum (hex)
9b537a5c008f7706b1183895b8de47a0a50e2991
schema:url
https://doi.org/10.1136/thoraxjnl-2020-215577
resource representing a document's title
Histopathological findings in fatal COVID-19 severe acute respiratory syndrome: preliminary experience from a series of 10 Spanish patients
has PubMed Central identifier
PMC7447113
has PubMed identifier
32839288
schema:publication
Thorax
resource representing a document's body
covid:9b537a5c008f7706b1183895b8de47a0a50e2991#body_text
is
schema:about
of
named entity 'Viral'
named entity 'patients'
named entity '2019'
named entity 'CYTOKINE STORM'
named entity 'China'
named entity 'paraffin'
named entity 'In December'
named entity 'biochemical markers'
named entity 'capillary'
named entity 'severe acute respiratory syndrome'
named entity 'Wuhan'
named entity 'histopathology'
named entity 'histopathological'
named entity 'Histopathological'
named entity 'COVID'
named entity 'histopathological'
named entity 'Capillary'
named entity 'T lymphocytes'
named entity 'hypertrophy'
named entity 'cytokine release syndrome'
named entity 'inflammation'
named entity 'pneumonitis'
named entity 'alveolar'
named entity 'low-molecular-weight heparin'
named entity 'risk of death'
named entity 'type II pneumocyte'
named entity 'diastolic'
named entity 'diffuse alveolar damage'
named entity 'infection'
named entity 'acute phase'
named entity 'tissue damage'
named entity 'SARS-COV-2'
named entity 'lung'
named entity 'COVID'
named entity 'cytokine release syndrome'
named entity 'lung'
named entity 'endothelial'
named entity 'inflammatory'
named entity 'troponin'
named entity 'infection'
named entity 'hyaline'
named entity 'prognosis'
named entity 'lung'
named entity 'myocardial cells'
named entity 'arterial thrombosis'
named entity 'heparin'
named entity 'inflammation'
named entity 'cardiac disease'
named entity 'disseminated intravascular coagulation'
named entity 'biopsies'
named entity 'SARS-CoV2'
named entity 'Postmortem'
named entity 'ultrasound'
named entity 'small intestine'
named entity 'COVID'
named entity 'lung'
named entity 'interstitial fibrosis'
named entity 'COVID'
named entity 'myocardiocytes'
named entity 'myocarditis'
named entity 'hyperplasia'
named entity 'SARS-CoV2'
named entity 'biopsies'
named entity 'immunosuppressive medication'
named entity 'RT-PCR'
named entity 'standard of care'
named entity 'DAD'
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