About: Upper gastrointestinal bleeding in COVID-19 inpatients: Incidence and management in a multicenter experience from Northern Italy

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About: Upper gastrointestinal bleeding in COVID-19 inpatients: Incidence and management in a multicenter experience from Northern Italy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Upper gastrointestinal bleeding in COVID-19 inpatients: Incidence and management in a multicenter experience from Northern Italy
Creator	Antonio, Sabatino, Di Marco, Pozzi Mauro, Aurelio Affiliations, Antonio Arnaldo, Amato Arnaldo, Dinelli Aurelio, Mauro Davide, Bardone Davide, Stradella De, Grazia Di, Sabatino Edoardo, Radaelli Edoardo, Savarino Elena, Elena, Strada Elisabetta, Filippi Elisabetta, Vecchi Federico, Federico, Marco Francesca, Ferretti Francesca, Filippi Franco, Bosani Franco, Radaelli Laura, Rovedatti Laura, Strada Lodovica, Pozzi Lodovica, Rovedatti Marco Vincenzo, Lenti Marco, Bardone Marco, Dinelli Marco, Ferretti Matteo, Bosani Matteo, Orlando Maurizio, Stradella Maurizio, Vecchi Roberto, Ardizzone Roberto, Frego Roberto, Penagini Sandro, Ardizzone Sandro, Savarino Stefania, Amato Stefania, Orlando Vincenzo, Penagini
Source	Elsevier; PMC
abstract	Abstract Background COVID-19 patients have an increased susceptibility to develop thrombotic complications, thus thromboprophylaxis is warranted which may increase risk of upper gastrointestinal bleeding (UGIB). Our aim was to evaluate incidence of UGIB and use of upper GI endoscopy in COVID-19 inpatients. Methods the medical and endoscopic management of UGIB in non-ICU COVID-19 patients has been retrospectively evaluated. Glasgow Blatchford score was calculated at onset of signs of GI bleeding. Timing between onset of signs of GI bleeding and execution, if performed, of upper GI endoscopy was evaluated. Endoscopic characteristics and outcome of patients were evaluated overall or according to the execution or not of an upper GI endoscopy before and after 24 hr. Results Out of 4871 COVID-19 positive patients, 23 presented signs of UGIB and were included in the study (incidence 0.47%). The majority (78%) were on anticoagulant therapy or thromboprophylaxis. In 11 patients (48%) upper GI endoscopy was performed within 24hr, whereas it was not performed in 5. Peptic ulcer was the most common finding (8/18). Mortality rate was 21.7% for worsening of COVID-19 infection. Mortality and rebleeding were not different between patients having upper GI endoscopy before or after 24 hr/not performed. Glasgow Blatchford score was similar between the two groups (13;12-16 vs 12;9-15). Conclusion Upper GI bleeding complicated hospital stay in almost 0.5% of COVID-19 patients and peptic ulcer disease is the most common finding. Conservative management could be an option in patients that are at high risk of respiratory complications.
has issue date	2020-08-14(xsd:dateTime)
bibo:doi	10.1016/j.clinre.2020.07.025
has license	els-covid
sha1sum (hex)	9c25aaa45153177e61221d9761f97a09444cefa2
schema:url	https://doi.org/10.1016/j.clinre.2020.07.025
resource representing a document's title	Upper gastrointestinal bleeding in COVID-19 inpatients: Incidence and management in a multicenter experience from Northern Italy
has PubMed Central identifier	PMC7427596
schema:publication	Clinics and Research in Hepatology and Gastroenterology
resource representing a document's body	covid:9c25aaa45153177e61221d9761f97a09444cefa2#body_text
is schema:about of	named entity 'upper GI endoscopy' named entity 'COVID-19' named entity 'endoscopy' named entity 'UGIB' named entity 'upper gastrointestinal bleeding' named entity 'COVID-19' named entity 'endoscopy' named entity 'UGIB' named entity 'GI bleeding' named entity 'thromboprophylaxis' named entity 'Upper gastrointestinal bleeding' named entity 'Upper gastrointestinal bleeding' named entity 'COVID' named entity 'critically ill patients' named entity 'COVID' named entity 'cirrhotic' named entity 'endoscopy' named entity 'COVID-19 hospitals' named entity 'type 1' named entity 'upper GI bleeding' named entity 'COVID' named entity 'Endoscopic' named entity 'UGIB' named entity 'COVID' named entity 'GBS' named entity 'ulcers' named entity 'endoscopic treatment' named entity 'UGIB' named entity 'multivariate analysis' named entity 'endoscopy' named entity 'endoscopy' named entity 'ICU beds' named entity 'antiplatelet therapy' named entity 'UGIB' named entity 'prophylaxis' named entity 'GBS' named entity 'respiratory support' named entity 'upper 1' named entity 'haemoglobin' named entity 'upper GI endoscopy'

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