About: Early Impact of COVID-19 on Solid Organ Transplantation in the United States

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About: Early Impact of COVID-19 on Solid Organ Transplantation in the United States Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Early Impact of COVID-19 on Solid Organ Transplantation in the United States
Creator	Ahmed, Aijaz Alshuwaykh, Omar Cholankeril, George Esquivel, Carlos Kanwal, Fasiha Kim, Donghee Podboy, Alexander
Source	Medline; PMC
abstract	The regional impact of coronavirus disease 2019 on solid organ transplantation in the United States has not been fully evaluated. METHODS. A retrospective analysis of month-to-month trends on waitlist additions, waitlist deaths, and transplant surgeries between all United Network for Organ Sharing (UNOS) regions was performed. A linear regression model trained on historical data was used to estimate anticipated transplantation volume. RESULTS. All UNOS regions reported a decrease in total waitlist additions and transplant surgeries. The largest decreases in total transplants were identified in regions 1, 2, 6, and 9, with regions 2, 7, 8, and 9 noting the largest decrease in waitlist additions. Six of the 11 regions noted increases in waitlist deaths, with UNOS regions 9, 1, and 2, all located within the Northeast, noting the highest percent increase in waitlist deaths at 170%, 89%, and 54%, respectively. The largest reductions in solid organ transplantation and waitlist deaths were seen in kidney and lung transplantation. Current transplantation volume is significantly lower than the low range of the 95% confidence interval derived from the linear regression model (2182 versus 3110; P < 0.05). CONCLUSIONS. Significant decreases in total waitlist additions and transplant surgeries with increases in waitlist deaths were noted in the majority of US transplant domains. The impact was especially prevalent in areas with high burden of coronavirus disease 2019 infection. National and regional strategies aimed at minimizing disruptions in transplantation are needed.
has issue date	2020-07-14(xsd:dateTime)
bibo:doi	10.1097/tp.0000000000003391
bibo:pmid	32675741
has license	no-cc
sha1sum (hex)	9d06751f46dd840744af37bd8870ea0b32fdf4b5
schema:url	https://doi.org/10.1097/tp.0000000000003391
resource representing a document's title	Early Impact of COVID-19 on Solid Organ Transplantation in the United States
has PubMed Central identifier	PMC7406203
has PubMed identifier	32675741
schema:publication	Transplantation
resource representing a document's body	covid:9d06751f46dd840744af37bd8870ea0b32fdf4b5#body_text
is schema:about of	named entity 'Impact' named entity 'United States' named entity 'COVID-19' named entity 'United States' named entity 'Month-to-month' named entity 'Kidney' named entity 'UNOS' named entity 'Wolters Kluwer Health' named entity 'liver' named entity 'month-to-month' named entity 'COVID-19 disease' named entity 'April 2020' named entity 'linear regression model' named entity 'solid organ transplantation' named entity 'COVID-19' named entity 'statistical analysis' named entity 'COVID-19 disease' named entity '2, 7, 8' named entity 'month-to-month' named entity 'COVID-19' named entity 'Lung' named entity 'lung transplantation' named entity 'kidney' named entity '95% CI' named entity 'UNOS' named entity 'solid organ transplantation' named entity 'Kidney' named entity 'lung transplants' named entity 'April 2020' named entity 'Boston' named entity 'Month-to-month' named entity 'UNOS' named entity 'SOT' named entity 'pancreas' named entity 'UNOS' named entity 'Wolters Kluwer Health' named entity 'historical data' named entity 'April 2020' named entity 'coronavirus disease 2019' named entity '95% confidence interval' named entity 'intestine' named entity 'April 30' named entity 'month-to-month' named entity 'kidney' named entity '2, 7, 8' named entity 'coronavirus disease 2019' named entity 'lung transplantation' named entity 'Month-to-month' named entity 'SOT' named entity 'linear regression model' named entity 'UNOS' named entity 'COVID-19' named entity 'R-squared' named entity 'lung' named entity '95% CI' named entity 'kidney' named entity 'kidney' named entity 'lung' named entity 'coronavirus disease 2019' named entity 'Lung' named entity 'United Network for Organ Sharing' named entity 'United States' named entity 'SOT' named entity 'kidney' named entity 'UNOS' named entity 'United States' named entity 'SOT' named entity 'liver' named entity 'Lung' named entity 'United States' named entity 'Kidney' named entity 'confounding' named entity 'COVID-19' named entity 'United Network for Organ Sharing' named entity 'regression model'

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