About: Age and Ebola viral load correlate with mortality and survival time in 288 Ebola virus disease patients

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About: Age and Ebola viral load correlate with mortality and survival time in 288 Ebola virus disease patients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Age and Ebola viral load correlate with mortality and survival time in 288 Ebola virus disease patients
Creator	Zhang, Jian Li, Jin Li, Lei Zhao, Min Zhang, Xin Wang, Ye Wang, Fu-Sheng Du, Ning Li, Chen Guo, Tong-Sheng Dong, Zheng Xu, Zhe Chen, Hao-Yang Duan, Hui-Juan Duan, Xue-Zhang Gao, Xu-Dong Ji, Dong Ji, Jun-Sheng Ji, Ying-Jie Jia, Hong-Jun Jiang, Tian-Jun Jin, Bo Li, Wen-Gang Li, Zhi-Wei Liu, Li-Ming Lu, Yin-Ying Mu, Jin-Song Nie, Wei-Min Qin, En-Qiang Rong, Yi-Hui Su, Hai-Bin Sun, Li-Jian Sun, Zhi-Qiang Teng, Guang-Ju Wang, Li-Fu Wang, Shu Yan, Tao Yuan, Yue Zhang, Ji-Yuan Zhuang, Ying-Jie Kanu, Alex Koroma, Sheku
source	Elsevier; Medline; PMC
abstract	BACKGROUND: A Chinese medical team managed Ebola virus disease (EVD) patients in Sierra Leone from October 2014 to March 2015 and attended to 693 suspected patients, of whom 288 had confirmed disease. METHODS: A retrospective study was conducted of the 288 patients with confirmed disease. Clinical symptoms, manifestations, and serum viral load were analyzed and compared among the different groups for mortality and survival time. RESULTS: Among the 288 confirmed EVD patients (149 male and 139 female, median age 28 years, and median log viral load 6.68), 98 died, 36 recovered, and 154 were lost to follow-up. Common symptoms were fever (77.78%), fatigue (64.93%), abdominal pain (64.58%), headache (62.85%), and diarrhea (61.81%). Compared to patients aged < 18 years, those who were older than 40 years had a higher probability of death (odds ratio 2.855, p = 0.044). Patients with a viral load of >10(6) copies/ml had a higher case fatality rate than those with <10(6) copies/ml (odds ratio 3.095, p = 0.004). Cox regression showed that age, viral load, and the presence of diarrhea correlated with mortality. CONCLUSION: Patients with a high viral load, of older age, and with diarrhea had a higher mortality and shorter survival time.
has issue date	2015-10-30(xsd:dateTime)
bibo:doi	10.1016/j.ijid.2015.10.021
bibo:pmid	26523640
has license	no-cc
sha1sum (hex)	9d0879c29e31def94fe498f40cb63fbf5b9323ab
schema:url	https://doi.org/10.1016/j.ijid.2015.10.021
resource representing a document's title	Age and Ebola viral load correlate with mortality and survival time in 288 Ebola virus disease patients
has PubMed Central identifier	PMC7110900
has PubMed identifier	26523640
schema:publication	Int J Infect Dis
resource representing a document's body	covid:9d0879c29e31def94fe498f40cb63fbf5b9323ab#body_text
is schema:about of	named entity 'survival' named entity 'Ebola virus disease' named entity 'Ebola' named entity 'EVD' named entity 'West Africa' named entity 'virus' named entity 'survival time' named entity 'viral load' named entity 'Kaplan-Meier' named entity 'diarrhea' named entity 'EVD' named entity 'Ebola' named entity 'China' named entity 'virus' named entity 'lactate Ringer's solution' named entity 'high-risk' named entity 'survival time' named entity 'EVD' named entity 'viral load' named entity 'intravenous' named entity 'diarrhea' named entity 'Chicago' named entity 'odds ratio' named entity 'Ebola' named entity 'critical role' named entity 'Ringer's solution' named entity 'Gaussian distribution' named entity 'fatality rate' named entity 'virus infection' named entity 'disinfection' named entity 'standard deviation' named entity 'infection' named entity 'NERC' named entity 'fatigue' named entity 'RT-PCR' named entity 'diarrhea' named entity 'vomiting' named entity 'epidemics' named entity 'PPE' named entity 'vomiting'

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