About: Structural studies on the Ebola virus matrix protein VP40 indicate that matrix proteins of enveloped RNA viruses are analogues but not homologues

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About: Structural studies on the Ebola virus matrix protein VP40 indicate that matrix proteins of enveloped RNA viruses are analogues but not homologues Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Structural studies on the Ebola virus matrix protein VP40 indicate that matrix proteins of enveloped RNA viruses are analogues but not homologues
Creator	Timmins, Joanna Weissenhorn, Winfried Ruigrok, Rob
Source	Elsevier
abstract	Abstract Matrix proteins are the driving force of assembly of enveloped viruses. Their main function is to interact with and polymerize at cellular membranes and link other viral components to the matrix–membrane complex resulting in individual particle shapes and ensuring the integrity of the viral particle. Although matrix proteins of different virus families show functional analogy, they share no sequence or structural homology. Their diversity is also evident in that they use a variety of late domain motifs to commit the cellular vacuolar protein sorting machinery to virus budding. Here, we discuss the structural and functional aspects of the filovirus matrix protein VP40 and compare them to other known matrix protein structures from vesicular stomatitis virus, influenza virus and retroviral matrix proteins.
has issue date	2004-04-15(xsd:dateTime)
bibo:doi	10.1016/j.femsle.2004.03.002
has license	els-covid
sha1sum (hex)	9e913d44d395e3e7a3d1a7d38559d8ab430bebbe
schema:url	https://doi.org/10.1016/j.femsle.2004.03.002
resource representing a document's title	Structural studies on the Ebola virus matrix protein VP40 indicate that matrix proteins of enveloped RNA viruses are analogues but not homologues
schema:publication	FEMS Microbiology Letters
resource representing a document's body	covid:9e913d44d395e3e7a3d1a7d38559d8ab430bebbe#body_text
is schema:about of	named entity 'protein' named entity 'aspects' named entity 'Here' named entity 'sorting' named entity 'Although' named entity 'homologues' named entity 'RNA VIRUSES' named entity 'INFLUENZA VIRUS' named entity 'PROTEIN STRUCTURES' named entity 'LATE' named entity 'PROTEINS' named entity 'INTEGRITY OF' named entity 'FUNCTION' named entity 'VIRAL PARTICLE' named entity 'MATRIX' named entity 'THEIR' named entity 'DIVERSITY' named entity 'FAMILIES' named entity 'MATRIX PROTEIN' named entity 'SHARE' named entity 'MAIN' named entity 'HERE' named entity 'PARTICLE' named entity 'ASSEMBLY' named entity 'VACUOLAR PROTEIN SORTING' named entity 'PROTEIN ' named entity 'STRUCTURAL' named entity 'RESULTING IN' named entity 'USE' named entity 'PROTEIN ' named entity 'DRIVING' named entity 'BUT' named entity 'STUDIES' named entity 'CELLULAR' named entity 'TO INTERACT WITH' named entity 'FUNCTIONAL' named entity 'SHAPES' named entity 'COMPARE' named entity 'VESICULAR STOMATITIS VIRUS' named entity 'KNOWN' named entity 'MACHINERY' named entity 'ANALOGY' named entity 'MEMBRANES' named entity 'STRUCTURAL HOMOLOGY' named entity 'DIFFERENT' named entity 'NO SEQUENCE' named entity 'RETROVIRAL' named entity 'COMMIT' named entity 'MOTIFS' named entity 'VIRUS BUDDING' named entity 'FILOVIRUS' named entity 'DOMAIN' named entity 'DISCUSS' named entity 'INDIVIDUAL' named entity 'VIRAL COMPONENTS' named entity 'COMPLEX' named entity 'STRUCTURAL' named entity 'PROTEINS' named entity 'FORCE' named entity 'VIRUSES' named entity 'VIRUS' named entity 'MATRIX' named entity 'EBOLA VIRUS' named entity 'MATRIX PROTEIN' named entity 'VARIETY' named entity 'LINK' named entity 'MEMBRANE' named entity 'protein' named entity 'analogy' named entity 'particle' named entity 'polymerize' named entity 'enveloped viruses' named entity 'retroviral' named entity 'domain motifs' named entity 'cellular membranes' named entity 'sequence or structural homology' named entity 'virus' named entity 'VP40' named entity 'influenza virus' named entity 'VP40' named entity 'Ebola virus' named entity 'homologues'

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