About: The early diversification of influenza A/H1N1pdm

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The early diversification of influenza A/H1N1pdm Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The early diversification of influenza A/H1N1pdm
Creator	Ghedin, Elodie Halpin, Rebecca Fan, Jiang Spiro, David Viboud, Cecile Proudfoot, Kathleen St. George, Kirsten Lin, Xudong Bera, Jayati Kumar, Swati Nelson, Martha Beck, Eric Bose, Michael Griesemer, Sara Henrickson, Kelly Hine, Erin Holmes, Edward Jurgens, Lisa Stockwell, Tim Wentworth, David
source	PMC
abstract	Background Since its initial detection in April 2009, the A/H1N1pdm influenza virus has spread rapidly in humans, with over 5,700 human deaths. However, little is known about the evolutionary dynamics of H1N1pdm and its geographic and temporal diversification. Methods Phylogenetic analysis was conducted upon the concatenated coding regions of whole-genome sequences from 290 H1N1pdm isolates sampled globally between April 1 – July 9, 2009, including relatively large samples from the US states of Wisconsin and New York. Results At least 7 phylogenetically distinct viral clades have disseminated globally and co-circulated in localities that experienced multiple introductions of H1N1pdm. The epidemics in New York and Wisconsin were dominated by two different clades, both phylogenetically distinct from the viruses first identified in California and Mexico, suggesting an important role for founder effects in determining local viral population structures. Conclusions Determining the global diversity of H1N1pdm is central to understanding the evolution and spatial spread of the current pandemic, and to predict its future impact on human populations. Our results indicate that H1N1pdm has already diversified into distinct viral lineages with defined spatial patterns.
has issue date	2009-11-12(xsd:dateTime)
bibo:doi	10.1371/currents.rrn1126
bibo:pmid	20029664
has license	cc-by
schema:url	https://doi.org/10.1371/currents.rrn1126
resource representing a document's title	The early diversification of influenza A/H1N1pdm
has PubMed Central identifier	PMC2773564
has PubMed identifier	20029664
schema:publication	PLoS Curr
resource representing a document's body	covid:PMC2773564#body_text
is schema:about of	named entity 'Clade' named entity 'Asia' named entity 'age distribution' named entity 'Eurasian' named entity 'clade' named entity 'virus' named entity 'influenza A virus' named entity 'viruses' named entity 'Clade' named entity 'sampling' named entity 'Asia' named entity 'Japan' named entity 'Canada' named entity 'MDCK' named entity 'H3N2' named entity 'virus' named entity 'Wisconsin' named entity 'Wisconsin' named entity 'viruses' named entity 'reassortant' named entity 'phylogenetic analysis' named entity 'real-time RT-PCR' named entity 'Arizona' named entity 'Bayesian' named entity 'NIAID' named entity 'Clade' named entity 'Rockville, MD' named entity 'CHW' named entity 'H1N1' named entity 'viruses' named entity 'Valencia, CA' named entity 'clades' named entity 'influenza' named entity 'sampling' named entity 'vary considerably' named entity 'virus' named entity 'clade' named entity 'Atlanta' named entity 'clades' named entity 'clade' named entity 'Wisconsin' named entity 'posterior probabilities' named entity 'clades' named entity 'genome' named entity 'amino acid' named entity 'Wisconsin' named entity 'assay' named entity 'clade' named entity 'amino acid' named entity 'clades' named entity 'transport medium' named entity 'Exonuclease' named entity 'real-time RT-PCR' named entity '500 million' named entity 'annealing' named entity 'TMRCA' named entity 'UPGMA' named entity 'clades' named entity 'China' named entity 'Wisconsin' named entity 'Wisconsin' named entity 'clinical samples' named entity 'MCMC'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software