About: Genetic variation analysis of reemerging porcine epidemic diarrhea virus prevailing in central China from 2010 to 2011

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About: Genetic variation analysis of reemerging porcine epidemic diarrhea virus prevailing in central China from 2010 to 2011 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Genetic variation analysis of reemerging porcine epidemic diarrhea virus prevailing in central China from 2010 to 2011
Creator	Zhao, Jun Chen, Lu Yang, Xia Wang, Chuan-qing Chang, Hong-tao Huo, Jin-yao Wang, Xin-wei Zheng, Feng-mei
source	Medline; PMC
abstract	Porcine epidemic diarrhea has re-emerged with devastating impact in central China since October 2010. To investigate and analyze the reason of this outbreak, the M and ORF3 genes of 15 porcine epidemic diarrhea viruses (PEDV), which were collected from different areas of central China during October 2010 and December 2011, were amplified by reverse transcriptase polymerase chain reaction, cloned, sequenced, and analyzed. Sequence analyses showed that the nucleotides and amino acids were changed at some sites in the M and ORF3 genes of the 15 PEDV strains compared with those genes of CV777 reference strain. Based on the phylogenetic analyses, PEDVs in central China and reference strains could be separated into three groups: G1, G2, and G3. The 15 PEDV strains belonged to G3 group and showed a close relationship with Korean strains (2007), Thai strains (2007–2008), and partial other Chinese strains (2010–2011), but differed genetically from European strains (Br1/87) and the vaccine strain (CV777 vs) being used in China. Furthermore, all 15 PEDV strains from central China and some other isolates in China from 2003 to 2007 (LJB-03, QH, and LZC) belonged to different group. Therefore, PEDV exhibits rapid variation and genetic evolution, and the currently prevailing PEDV strains in central China are a new genotype.
has issue date	2012-12-27(xsd:dateTime)
bibo:doi	10.1007/s11262-012-0867-x
bibo:pmid	23269482
has license	cc-by
schema:url	https://doi.org/10.1007/s11262-012-0867-x
resource representing a document's title	Genetic variation analysis of reemerging porcine epidemic diarrhea virus prevailing in central China from 2010 to 2011
has PubMed Central identifier	PMC3610022
has PubMed identifier	23269482
schema:publication	Virus Genes
resource representing a document's body	covid:PMC3610022#body_text
is schema:about of	named entity 'Genetic variation' named entity 'GENETIC VARIATION ANALYSIS' named entity '2011' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'CENTRAL' named entity 'CHINA' named entity 'porcine epidemic diarrhea virus' named entity 'PEDV' named entity 'Group 3' named entity 'TGEV' named entity 'PEDV' named entity 'gene' named entity 'kDa' named entity 'molecular weight' named entity 'amino acid' named entity 'virus' named entity 'highly contagious' named entity 'serum' named entity 'China' named entity 'amino acid sequences' named entity 'sequence analysis' named entity 'genome' named entity 'Henan' named entity 'PEDV' named entity 'transmissible gastroenteritis virus' named entity 'dehydration' named entity 'KFQX' named entity 'nucleotide' named entity 'Phylogenetic analysis' named entity 'PEDV' named entity 'ORFs' named entity 'PEDV' named entity 'agarose gel' named entity 'gene' named entity 'sequence identity' named entity 'Hebei' named entity 'gene' named entity 'gene' named entity 'piglet' named entity '3′ UTR' named entity 'gene' named entity 'PCR' named entity 'vaccine' named entity 'pmol' named entity 'PEDV' named entity 'Henan' named entity 'protein' named entity 'virus' named entity 'Korea' named entity 'amino acid' named entity 'diarrhea' named entity '5′ untranslated region' named entity 'evolution' named entity 'China' named entity 'epidemic' named entity '100 %' named entity 'open reading frames' named entity 'Beijing Genomics Institute' named entity 'cloned' named entity 'gene' named entity 'pig' named entity 'nucleotide' named entity 'virulence gene' named entity 'diarrhea' named entity 'amino acid' named entity 'nonstructural proteins' named entity 'China' named entity 'PEDV' named entity 'severe diarrhea' named entity '2 and 1' named entity 'gene' named entity 'PEDV' named entity 'virulence' named entity 'kDa' named entity 'Thailand'

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