About: Intraoperative adverse events and early outcomes of custom-made fenestrated stent grafts and physician-modified stent grafts for complex aortic aneurysms

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About: Intraoperative adverse events and early outcomes of custom-made fenestrated stent grafts and physician-modified stent grafts for complex aortic aneurysms Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Intraoperative adverse events and early outcomes of custom-made fenestrated stent grafts and physician-modified stent grafts for complex aortic aneurysms
Creator	Cochennec, Frédéric Desgranges, Pascal Kobeiter, Hicham Becquemin, Jean-Pierre Ben Abdallah, Iannis Touma, Joseph de Boissieu, Paul Sénémaud, Jean
Source	PMC
abstract	OBJECTIVE: Physician-modified fenestrated stent grafts (PMSGs) are a useful option for urgent or semiurgent treatment of complex abdominal aortic aneurysms (CAAAs). The aim of this study was to describe in-hospital outcomes of custom-made fenestrated stent grafts (CMSGs) and PMSGs for the treatment of CAAAs and thoracoabdominal aortic aneurysms (TAAAs). METHODS: In this single-center, retrospective study, all consecutives patients with CAAAs or TAAAs undergoing endovascular repair using Zenith CMSGs (Cook Medical, Bloomington, Ind) or PMSGs between January 2012 and November 2017 were included. End points were intraoperative adverse events, in-hospital mortality, postoperative complications, reinterventions, target vessel patency, and endoleaks. RESULTS: Ninety-seven patients were included (CMSGs, n = 69; PMSGs, n = 28). The PMSG group included more patients assigned to American Society of Anesthesiologists class 4 (n = 14 [50%] vs n = 16 [23%]; P = .006) and more TAAAs (n = 17 [61%] vs n = 10 [15%]; P < .0001). Intraoperative adverse events were recorded in eight (11%) patients in the CMSG group vs six (21%) patients in the PMSG group. No intraoperative death or open conversion occurred. In-hospital mortality rates were of 4% (n = 3) in the CMSG group and 14% in the PMSG group (n = 4). Chronic renal failure was an independent preoperative risk factor of postoperative death or complications (odds ratio, 4.88; 95% confidence interval, 1.65-14.43; P = .004). Rates of postoperative complications were 22% (n = 15) and 25% (n = 7) in the CMSG and PMSG groups. Spinal cord ischemia rates were 4% (n = 3) and 7% (n = 2) in the CMSG and PMSG groups. Reintervention rates were 16% (n = 11) in the CMSG group and 32% (n = 9) in the PMSG group. At discharge, target vessel patency rate in CMSGs was 98% (n = 207/210). All target vessels (n = 98) were patent in the PMSG group. Endoleaks at discharge were observed in 24% of the CMSG group (n = 16) vs 8% of the PMSG group (n = 2). CONCLUSIONS: Our study showed clinically relevant differences of several important in-hospital outcomes in the CMSG and PMSG groups. Larger cohorts and longer follow-up are needed to allow direct comparison. PMSGs may offer acceptable in-hospital results in patients requiring urgent interventions when CMSGs are not available or possible.
has issue date	2019-11-07(xsd:dateTime)
bibo:doi	10.1016/j.jvs.2019.07.102
bibo:pmid	31708298
has license	no-cc
schema:url	https://doi.org/10.1016/j.jvs.2019.07.102
resource representing a document's title	Intraoperative adverse events and early outcomes of custom-made fenestrated stent grafts and physician-modified stent grafts for complex aortic aneurysms
has PubMed Central identifier	PMC7126501
has PubMed identifier	31708298
schema:publication	J Vasc Surg
resource representing a document's body	covid:PMC7126501#body_text
is schema:about of	named entity 'Intraoperative' named entity 'stent' named entity 'pleural effusion' named entity 'high-risk' named entity 'Amplatzer' named entity 'stents' named entity 'ulcer' named entity 'PMSG' named entity 'cannulation' named entity 'Rastatt' named entity 'metabolic equivalent of task' named entity 'PMSG' named entity 'Spinal cord' named entity 'EVAR' named entity 'proximal and distal' named entity 'Aneurysms' named entity 'stent graft' named entity 'mortality rate' named entity 'renal arteries' named entity 'endoleak' named entity 'PMSG' named entity 'ulcer' named entity 'stent' named entity 'medical history' named entity 'PMSG' named entity 'PMSG' named entity 'superior mesenteric artery' named entity 'aneurysms' named entity 'aneurysms' named entity 'PMSG' named entity 'PMSG' named entity 'stents' named entity 'stenting' named entity 'PMSG' named entity 'Aneurysm' named entity 'SAS' named entity 'PMSG' named entity 'PMSG' named entity 'endoleak' named entity 'endoleak' named entity 'paraplegia' named entity 'Declaration of Helsinki' named entity 'mortality rate' named entity 'neurologic' named entity 'thoracic aorta' named entity 'stents' named entity 'renal arteries' named entity 'aneurysms' named entity 'stent' named entity 'standard deviation' named entity 'meta-analysis' named entity 'renal failure' named entity 'computed tomography (CT) scan' named entity 'high-risk' named entity 'follow-up' named entity 'mortality rate' named entity 'open repair' named entity 'saccular aneurysms' named entity 'aneurysms' named entity 'confidence intervals' named entity 'adverse events' named entity 'Tempe' named entity 'PMSG' named entity 'American Society of Anesthesiologists' named entity 'risks and benefits' named entity 'PMSG' named entity 'aneurysms' named entity 'luminal' named entity 'PMSG' named entity 'early death' named entity 'aneurysms' named entity 'renal arteries' named entity '70 mm' named entity 'retrospective study' named entity 'Cary, NC'

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