About: Highly sensitive fluorogenic sensing of L-Cysteine in live cells using gelatin-stabilized gold nanoparticles decorated graphene nanosheets

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About: Highly sensitive fluorogenic sensing of L-Cysteine in live cells using gelatin-stabilized gold nanoparticles decorated graphene nanosheets Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Highly sensitive fluorogenic sensing of L-Cysteine in live cells using gelatin-stabilized gold nanoparticles decorated graphene nanosheets
Creator	Liang, Po-Huang Chen, Shen-Ming Chen, Tse-Wei Dhenadhayalan, Namasivayam Lin, King-Chuen Liu, Yan-Jin Thirumalraj, Balamurugan
Source	Elsevier; Medline; PMC
abstract	A highly sensitive and selective fluorogenic sensing of L-Cysteine (L-Cys) was implemented based on gelatin stabilized gold nanoparticles decorated reduced graphene oxide (rGO/Au) nanohybrid. The rGO/Au nanohybrid was prepared by the one-pot hydrothermal method and well characterized by different physiochemical techniques. The nanohybrid exhibits a weak fluorescence of rGO due to the energy transfer from the rGO to Au NPs. The rGO/Au nanohybrid shows enhanced fluorescence activity due to the restoration of quenched fluorescence of rGO/Au nanohybrid in presence of L-Cys. The rGO/Au nanohybrid exhibits much lower detection limit of 0.51 nM for L-Cys with higher selectivity. The fluorescence sensing mechanism arose from the fluorescence recovery due to the stronger interaction between Au NPs and L-Cys, and consequently, the energy transfer was prevented between rGO and Au NPs. The practicability of rGO/Au sensor was implemented by invitro bioimaging measurements in Colo-205 (colorectal adenocarcinoma) and MKN-45 (gastric carcinoma) cancer live cells with excellent biocompatibility.
has issue date	2018-04-15(xsd:dateTime)
bibo:doi	10.1016/j.snb.2017.12.028
bibo:pmid	32288250
has license	no-cc
schema:url	https://doi.org/10.1016/j.snb.2017.12.028
resource representing a document's title	Highly sensitive fluorogenic sensing of L-Cysteine in live cells using gelatin-stabilized gold nanoparticles decorated graphene nanosheets
has PubMed Central identifier	PMC7127153
has PubMed identifier	32288250
schema:publication	Sens Actuators B Chem
resource representing a document's body	covid:PMC7127153#body_text
is schema:about of	named entity 'nanosheets' named entity 'graphene' named entity 'fluorescence intensity' named entity 'L-Cys' named entity 'fluorescence intensity' named entity 'sensor' named entity 'fluorescence' named entity 'energy transfer' named entity 'L-Cys' named entity 'L-Cys' named entity 'sensor' named entity 'biomolecules' named entity 'L-Cys' named entity 'assay' named entity 'spectroscopy' named entity 'L-Cys' named entity 'Leica' named entity 'live cells' named entity 'graphite oxide' named entity 'L-Cys' named entity 'peptide' named entity 'IR spectroscopy' named entity 'HPLC' named entity 'bovine' named entity 'ground state' named entity 'spectrometer' named entity 'spectrophotometer' named entity 'oxygen' named entity 'skin lesions' named entity 'biomolecule' named entity 'fat loss' named entity 'TEM' named entity 'wt%' named entity 'fluorescence' named entity 'graphite oxide' named entity 'L-Cys' named entity 'spectra' named entity 'spectra' named entity 'fluorescence intensity' named entity 'NaOH solution' named entity 'thiol group' named entity 'absorption spectra' named entity 'absorbance' named entity 'slow growth' named entity 'L-Cys' named entity 'absorption peak' named entity 'L-Cys' named entity 'NPs' named entity 'denatured' named entity 'Veeco' named entity 'L-Cys' named entity 'cancer cells' named entity 'Lys' named entity 'Raman' named entity 'light source' named entity 'fluorescence' named entity 'live cells' named entity 'NPs' named entity 'biomolecules' named entity 'homeostasis' named entity 'biomedical applications' named entity 'β-alanine' named entity 'L-Cys' named entity 'NPs' named entity 'graphite oxide' named entity 'cell culture media' named entity 'L-arginine' named entity 'fluorescence' named entity 'DPBS' named entity 'live cells' named entity 'L-Cys' named entity 'L-Cys' named entity 'fluorescence' named entity 'fluorescence' named entity 'surface area' named entity 'L-Cysteine'

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