About: TRPV4: A Physio and Pathophysiologically Significant Ion Channel

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	TRPV4: A Physio and Pathophysiologically Significant Ion Channel
Creator	Benítez-Angeles, Miguel Hiriart, Marcia Morales-Buenrostro, Luis Morales-Lázaro, Sara Rosenbaum, Tamara Sánchez-Hernández, Raúl Torres-Quiroz, Francisco
Source	Medline; PMC
abstract	Transient Receptor Potential (TRP) channels are a family of ion channels whose members are distributed among all kinds of animals, from invertebrates to vertebrates. The importance of these molecules is exemplified by the variety of physiological roles they play. Perhaps, the most extensively studied member of this family is the TRPV1 ion channel; nonetheless, the activity of TRPV4 has been associated to several physio and pathophysiological processes, and its dysfunction can lead to severe consequences. Several lines of evidence derived from animal models and even clinical trials in humans highlight TRPV4 as a therapeutic target and as a protein that will receive even more attention in the near future, as will be reviewed here.
has issue date	2020-05-28(xsd:dateTime)
bibo:doi	10.3390/ijms21113837
bibo:pmid	32481620
has license	cc-by
sha1sum (hex)	a080369435be19acd9feb57e62e2b610d2c78569
schema:url	https://doi.org/10.3390/ijms21113837
resource representing a document's title	TRPV4: A Physio and Pathophysiologically Significant Ion Channel
has PubMed Central identifier	PMC7312103
has PubMed identifier	32481620
schema:publication	Int J Mol Sci
resource representing a document's body	covid:a080369435be19acd9feb57e62e2b610d2c78569#body_text
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