About: Demonstration of a Glycoprotein Derived From the Ceacam10 Gene in Mouse Seminal Vesicle Secretions(1)

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About: Demonstration of a Glycoprotein Derived From the Ceacam10 Gene in Mouse Seminal Vesicle Secretions(1) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Demonstration of a Glycoprotein Derived From the Ceacam10 Gene in Mouse Seminal Vesicle Secretions(1)
Creator	Chen, Yee-Hsiung Hsiao, Ya-Ling Lee, Kuo-Kuang Li, Sheng-Hsiang
Source	PMC
abstract	CEACAM10 was purified from mouse seminal vesicle secretions by a series of purification steps that included ion exchange chromatography on a DEAE-Sephacel column and ion exchange high-performance liquid chromatography on a sulfopropyl column. It was shown to be a 36-kDa glycoprotein with an N-linked carbohydrate moiety. The circular dichromoism spectrum of CEACAM10 in 50 mM phosphate buffer at pH 7.4 appeared as one negative band arising from the β form at 217 nm. CEACAM10 was expressed predominantly in seminal vesicles of adult mice. Both CEACAM10 and its mRNA were demonstrated on the luminal epithelium of the mucosal folds in the seminal vesicle. The amount of Ceacam10 mRNA in the seminal vesicle was correlated with the stage of animal maturation. Castration of adult mice resulted in cessation of Ceacam10 expression, while treatment of castrated mice with testosterone propionate in corn oil restored Ceacam10 expression in the seminal vesicle. During the entire course of pregnancy, Ceacam10 might be silent in the embryo. A cytochemical study illustrated the presence of the CEACAM10 binding region on the entire surface of mouse sperm. CEACAM10-sperm binding greatly enhanced sperm motility in vitro.
has issue date	2005-09-01(xsd:dateTime)
bibo:doi	10.1095/biolreprod.105.039651
bibo:pmid	15901639
has license	no-cc
sha1sum (hex)	a149b2f9bea8d1613f854c545d192ab142e8dfaf
schema:url	https://doi.org/10.1095/biolreprod.105.039651
resource representing a document's title	Demonstration of a Glycoprotein Derived From the Ceacam10 Gene in Mouse Seminal Vesicle Secretions(1)
has PubMed Central identifier	PMC7109865
has PubMed identifier	15901639
schema:publication	Biol Reprod
resource representing a document's body	covid:a149b2f9bea8d1613f854c545d192ab142e8dfaf#body_text
is schema:about of	named entity 'SECRETIONS' named entity 'During' named entity 'testosterone propionate' named entity 'sperm motility' named entity 'GENE' named entity 'SPERM MOTILITY' named entity 'CARBOHYDRATE MOIETY' named entity 'COURSE' named entity 'TREATMENT' named entity 'PH 7.4' named entity 'SPECTRUM' named entity 'CIRCULAR' named entity 'FORM' named entity 'LIQUID CHROMATOGRAPHY ' named entity 'SEMINAL VESICLES' named entity 'MOUSE' named entity 'SPERM' named entity 'SERIES' named entity 'PRESENCE OF' named entity 'HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY' named entity 'GLYCOPROTEIN' named entity 'ARISING' named entity 'PHOSPHATE BUFFER' named entity 'NEGATIVE' named entity 'STUDY' named entity 'SILENT' named entity 'MRNA' named entity 'GREATLY' named entity 'FOLDS' named entity 'SURFACE' named entity 'DEAE' covid:arg/a149b2f9bea8d1613f854c545d192ab142e8dfaf named entity 'CEACAM10' named entity 'MOUSE SEMINAL VESICLE' named entity 'SECRETIONS' named entity 'CESSATION' named entity 'CORN OIL' named entity 'DEMONSTRATION' named entity 'MUCOSAL' named entity 'PREGNANCY' named entity 'INCLUDED' named entity 'PURIFICATION' named entity 'STEPS' named entity '90%' named entity 'ENTIRE' named entity 'MATURATION' named entity 'TESTOSTERONE PROPIONATE' named entity 'BINDING' named entity 'IN VITRO' named entity 'STAGE' named entity 'GLYCOPROTEIN' named entity 'EXPRESSION' named entity 'EPITHELIUM' named entity 'TRANSPORT' named entity 'ION EXCHANGE' named entity 'MICE' named entity 'SEMINAL VESICLE' named entity 'CEA' named entity 'MOUSE SEMINAL VESICLE' named entity 'ENHANCED' named entity 'CEACAM10' named entity 'BINDING REGION' named entity 'CASTRATED' named entity 'CASTRATION' named entity 'DERIVED' named entity 'BAND' named entity 'KDA' named entity 'EXPRESSED' named entity 'EMBRYO' named entity 'MIGHT BE' named entity 'DEMONSTRATED' named entity 'PURIFIED' named entity 'CORRELATED' named entity 'ION EXCHANGE CHROMATOGRAPHY' named entity 'COLUMN' named entity 'ADULT' named entity '217' named entity 'ANIMAL'

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