About: Diseases and Molecular Diagnostics: A Step Closer to Precision Medicine

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Diseases and Molecular Diagnostics: A Step Closer to Precision Medicine Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Diseases and Molecular Diagnostics: A Step Closer to Precision Medicine
Creator	Dwivedi, Shailendra Goel, Apul Khattri, Sanjay Misra, Radhieka Misra, Sanjeev Kamlesh, • Pant, Kumar Pareek, • Praveen, • Purohit, •
source	Medline; PMC
abstract	The current advent of molecular technologies together with a multidisciplinary interplay of several fields led to the development of genomics, which concentrates on the detection of pathogenic events at the genome level. The structural and functional genomics approaches have now pinpointed the technical challenge in the exploration of disease-related genes and the recognition of their structural alterations or elucidation of gene function. Various promising technologies and diagnostic applications of structural genomics are currently preparing a large database of disease-genes, genetic alterations etc., by mutation scanning and DNA chip technology. Further the functional genomics also exploring the expression genetics (hybridization-, PCR- and sequence-based technologies), two-hybrid technology, next generation sequencing with Bioinformatics and computational biology. Advances in microarray “chip” technology as microarrays have allowed the parallel analysis of gene expression patterns of thousands of genes simultaneously. Sequence information collected from the genomes of many individuals is leading to the rapid discovery of single nucleotide polymorphisms or SNPs. Further advances of genetic engineering have also revolutionized immunoassay biotechnology via engineering of antibody-encoding genes and the phage display technology. The Biotechnology plays an important role in the development of diagnostic assays in response to an outbreak or critical disease response need. However, there is also need to pinpoint various obstacles and issues related to the commercialization and widespread dispersal of genetic knowledge derived from the exploitation of the biotechnology industry and the development and marketing of diagnostic services. Implementation of genetic criteria for patient selection and individual assessment of the risks and benefits of treatment emerges as a major challenge to the pharmaceutical industry. Thus this field is revolutionizing current era and further it may open new vistas in the field of disease management.
has issue date	2017-08-22(xsd:dateTime)
bibo:doi	10.1007/s12291-017-0688-8
bibo:pmid	29062170
has license	bronze-oa
sha1sum (hex)	a27094a922d8f9bd30eda09f9f9ea78f43e7fa3c
schema:url	https://doi.org/10.1007/s12291-017-0688-8
resource representing a document's title	Diseases and Molecular Diagnostics: A Step Closer to Precision Medicine
has PubMed Central identifier	PMC5634985
has PubMed identifier	29062170
schema:publication	Indian Journal of Clinical Biochemistry
resource representing a document's body	covid:a27094a922d8f9bd30eda09f9f9ea78f43e7fa3c#body_text
is schema:about of	named entity 'However' named entity 'Biotechnology' named entity 'DNA chip' named entity 'genetic engineering' named entity 'alterations' named entity 'commercialization' named entity 'biotechnology' named entity 'patterns' named entity 'A MAJOR' named entity 'STRUCTURAL GENOMICS' named entity 'GENE FUNCTION' named entity 'RISKS' named entity 'ALTERATIONS' named entity 'GENETIC' named entity 'GENOME' named entity 'NEXT GENERATION SEQUENCING' named entity 'EVENTS' named entity 'VARIOUS' named entity 'LED' named entity 'SIMULTANEOUSLY' named entity 'DETECTION' named entity 'EXPRESSION' named entity 'EXPLORATION' named entity 'PATIENT SELECTION' named entity 'BASED' named entity 'DISPERSAL' named entity 'ROLE' named entity 'OPEN' named entity 'RESPONSE TO' named entity 'DISCOVERY' named entity 'SCANNING' named entity 'SEQUENCE' named entity 'PATHOGENIC' named entity 'MICROARRAY' named entity 'EXPLORING' named entity 'BIOTECHNOLOGY' named entity 'APPLICATIONS' named entity 'ISSUES' named entity 'ETC.' named entity 'INDUSTRY' named entity 'ALLOWED' named entity 'PLAYS' named entity 'CRITERIA' named entity 'ASSESSMENT' named entity 'DIAGNOSTIC' named entity 'DISEASE' named entity 'GENE EXPRESSION' named entity 'LEADING' named entity 'DATABASE' named entity 'DIAGNOSTIC SERVICES' named entity 'MULTIDISCIPLINARY' named entity 'INDIVIDUAL' named entity 'OUTBREAK' named entity 'GENES' named entity 'LEVEL' named entity 'WIDESPREAD' named entity 'COLLECTED' named entity 'PCR' named entity 'ENCODING' named entity 'CURRENT' named entity 'GENETIC ENGINEERING' named entity 'PHAGE DISPLAY' named entity 'SNPS' named entity 'INDIVIDUALS' named entity 'APPROACHES' named entity 'NEED' named entity 'PHARMACEUTICAL INDUSTRY' named entity 'DNA CHIP' named entity 'ENGINEERING' named entity 'ANALYSIS' named entity 'PARALLEL' named entity 'FUNCTIONAL GENOMICS'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software