About: The importance of dog population contact network structures in rabies transmission

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The importance of dog population contact network structures in rabies transmission Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The importance of dog population contact network structures in rabies transmission
Creator	Zinsstag, Jakob Smieszek, Timo Chitnis, Nakul Laager, Mirjam Mbilo, Céline Naminou, Abakar Lie Tschopp, Auré Lé Chenne, Monique Madaye, Enos Naïssengar, Service
Source	Medline; PMC
abstract	Canine rabies transmission was interrupted in N’Djaména, Chad, following two mass vaccination campaigns. However, after nine months cases resurged with re-establishment of endemic rabies transmission to pre-intervention levels. Previous analyses investigated district level spatial heterogeneity of vaccination coverage, and dog density; and importation, identifying the latter as the primary factor for rabies resurgence. Here we assess the impact of individual level heterogeneity on outbreak probability, effectiveness of vaccination campaigns and likely time to resurgence after a campaign. Geo-located contact sensors recorded the location and contacts of 237 domestic dogs in N’Djaména over a period of 3.5 days. The contact network data showed that urban dogs are socially related to larger communities and constrained by the urban architecture. We developed a network generation algorithm that extrapolates this empirical contact network to networks of large dog populations and applied it to simulate rabies transmission in N’Djaména. The model predictions aligned well with the rabies incidence data. Using the model we demonstrated, that major outbreaks are prevented when at least 70% of dogs are vaccinated. The probability of a minor outbreak also decreased with increasing vaccination coverage, but reached zero only when coverage was near total. Our results suggest that endemic rabies in N’Djaména may be explained by a series of importations with subsequent minor outbreaks. We show that highly connected dogs hold a critical role in transmission and that targeted vaccination of such dogs would lead to more efficient vaccination campaigns.
has issue date	2018-08-01(xsd:dateTime)
bibo:doi	10.1371/journal.pntd.0006680
bibo:pmid	30067733
has license	cc-by
sha1sum (hex)	a3436bd86402190ee99045fd5a87c277288d585a
schema:url	https://doi.org/10.1371/journal.pntd.0006680
resource representing a document's title	The importance of dog population contact network structures in rabies transmission
has PubMed Central identifier	PMC6089439
has PubMed identifier	30067733
schema:publication	PLoS Negl Trop Dis
resource representing a document's body	covid:a3436bd86402190ee99045fd5a87c277288d585a#body_text
is schema:about of	named entity 'spatial heterogeneity' named entity 'targeted' named entity 'outbreaks' named entity 'predictions' named entity 'probability' named entity 'analyses' covid:arg/a3436bd86402190ee99045fd5a87c277288d585a named entity 'developed' named entity 'populations' named entity 'lead' named entity 'subsequent' named entity 'highly' named entity 'demonstrated' named entity 'large' named entity 'contact' named entity 'time' named entity 'vaccination' named entity 'coverage' named entity 'series' named entity 'Chad' named entity 'investigated' named entity 'rabies' named entity 'N'Djaména' named entity 'dog' named entity 'rabies' named entity 'vaccination' named entity 'vaccination' named entity 'network structures' named entity 'rabies' named entity 'Poisson distribution' named entity 'Vaccination' named entity 'incubation period' named entity 'rabies' named entity 'sensitivity analysis' named entity 'rabies' named entity 'rabies' named entity 'vaccination campaign' named entity 'Australia' named entity 'N'Djaména' named entity 'mammals' named entity 'viral disease' named entity 'individual based models' named entity 'rabies' named entity 'N'Djaména' named entity 'connected component' named entity 'rabies' named entity 'vaccination' named entity 'rabid dogs' named entity 'human immunodeficiency virus' named entity 'rabies' named entity 'rabies' named entity 'infectious disease' named entity 'rabies' named entity 'rabies' named entity 'degree centrality' named entity 'deterministic' named entity 'community transmission' named entity 'dry season' named entity 'betweenness centrality' named entity 'rabies' named entity 'algorithm' named entity 'rabies' named entity 'contact structure' named entity 'algorithm' named entity 'algorithm' named entity '3.5' named entity 'probability' named entity 'rabies' named entity 'N'Djaména' named entity 'oral vaccine' named entity '60,000' named entity 'probability'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software