About: Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy

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About: Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy
Creator	Wu, Han-Chung Chang, De-Kuan
Source	PMC
abstract	Solid tumors are known to recruit new blood vessels to support their growth. Therefore, unique molecules expressed on tumor endothelial cells can function as targets for the antiangiogenic therapy of cancer. Current efforts are focusing on developing therapeutic agents capable of specifically targeting cancer cells and tumor-associated microenvironments including tumor blood vessels. These therapies hold the promise of high efficacy and low toxicity. One recognized strategy for improving the therapeutic effectiveness of conventional chemotherapeutics is to encapsulate anticancer drugs into targeting liposomes that bind to the cell surface receptors expressed on tumor-associated endothelial cells. These anti-angiogenic drug delivery systems could be used to target both tumor blood vessels as well as the tumor cells, themselves. This article reviews the mechanisms and advantages of various present and potential methods using peptide-conjugated liposomes to specifically destroy tumor blood vessels in anticancer therapy.
has issue date	2010-05-05(xsd:dateTime)
bibo:doi	10.1155/2010/723798
bibo:pmid	20454584
has license	cc-by
sha1sum (hex)	a4ee99345c99a1f9806c8d17dc7e6accaf5309d6
schema:url	https://doi.org/10.1155/2010/723798
resource representing a document's title	Peptide-Mediated Liposomal Drug Delivery System Targeting Tumor Blood Vessels in Anticancer Therapy
has PubMed Central identifier	PMC2864512
has PubMed identifier	20454584
schema:publication	J Oncol
resource representing a document's body	covid:a4ee99345c99a1f9806c8d17dc7e6accaf5309d6#body_text
is schema:about of	named entity 'BLOOD VESSELS' named entity 'bind' named entity 'strategy' named entity 'tumor cells' named entity 'liposomes' named entity 'Therapy' named entity 'TUMOR' named entity 'LIPOSOMAL' named entity 'DRUG DELIVERY SYSTEM' named entity 'KNOWN' named entity 'THESE' named entity 'POTENTIAL' named entity 'TARGETING' named entity 'THERAPIES' named entity 'COULD BE' named entity 'DRUGS' named entity 'CANCER' named entity 'TARGETS' named entity 'EFFECTIVENESS' named entity 'NEW' named entity 'BLOOD VESSELS' named entity 'HOLD' named entity 'FUNCTION' named entity 'CURRENT' named entity 'TARGET' named entity 'CONJUGATED' named entity 'IMPROVING' named entity 'MECHANISMS' named entity 'LIPOSOMES' named entity 'EXPRESSED' named entity 'STRATEGY' named entity 'UNIQUE' named entity 'RECEPTORS' named entity 'VARIOUS' named entity 'TO SUPPORT' named entity 'PEPTIDE' named entity 'TUMOR' named entity 'CAPABLE' named entity 'BIND' named entity 'GROWTH' named entity 'ANTIANGIOGENIC THERAPY' named entity 'ARTICLE' named entity 'DESTROY' named entity 'ASSOCIATED' named entity 'THERAPEUTIC' named entity 'THE CELL' named entity 'ANGIOGENIC' named entity 'USED' named entity 'MOLECULES' named entity 'PEPTIDE' named entity 'ENCAPSULATE' named entity 'ANTICANCER THERAPY' named entity 'INCLUDING' named entity 'PROMISE' named entity 'DRUG DELIVERY SYSTEMS' named entity 'USING' named entity 'FOCUSING' named entity 'CHEMOTHERAPEUTICS' named entity 'TARGETING' named entity 'CONVENTIONAL' named entity 'CANCER CELLS' named entity 'THERAPEUTIC AGENTS' named entity 'SOLID TUMORS' named entity 'EFFICACY' named entity 'ENDOTHELIAL CELLS' named entity 'METHODS' named entity 'ANTICANCER THERAPY' named entity 'PRESENT' named entity 'MEDIATED' named entity 'HIGH' named entity 'DEVELOPING' named entity 'ANTICANCER' named entity 'REVIEWS' named entity 'CELL SURFACE' named entity 'LOW TOXICITY' named entity 'TUMOR CELLS' named entity 'THEIR' covid:arg/a4ee99345c99a1f9806c8d17dc7e6accaf5309d6 named entity 'drug delivery systems' named entity 'anticancer drugs'

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