About: Global Spread of Coronavirus Disease 2019 and Malaria: An Epidemiological Paradox in the Early Stage of A Pandemic

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About: Global Spread of Coronavirus Disease 2019 and Malaria: An Epidemiological Paradox in the Early Stage of A Pandemic Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Global Spread of Coronavirus Disease 2019 and Malaria: An Epidemiological Paradox in the Early Stage of A Pandemic
Creator	Napoli, Pietro Nioi, Matteo
Source	Medline; PMC; WHO
abstract	In the current work, we discovered and analyzed the epidemiological paradox between coronavirus disease 2019 (COVID-19) and malaria in the initial phase of the ongoing pandemic. From the analysis of distribution data, the endemic presence of malaria seems to protect some populations from COVID-19 outbreak, particularly in the least developed countries. In this sense, molecular and genetic variations associated with malaria (e.g., in ACE2) might play a protective role against coronavirus infection. Moreover, the mechanism of action of some antimalarial drugs, e.g., the antiviral function, suggests their potential role in the chemoprophylaxis of coronavirus epidemics, despite possible adverse effects (e.g., retinal toxicity). All these data provide important insights to understand the spreading mechanisms of COVID-19, and to direct scientific research toward the study of some currently available medications.
has issue date	2020-04-16(xsd:dateTime)
bibo:doi	10.3390/jcm9041138
bibo:pmid	32316118
has license	cc-by
sha1sum (hex)	a4fdd6a62dce7a973ee523cd8b916abdbaedc1ba
schema:url	https://doi.org/10.3390/jcm9041138
resource representing a document's title	Global Spread of Coronavirus Disease 2019 and Malaria: An Epidemiological Paradox in the Early Stage of A Pandemic
has PubMed Central identifier	PMC7230338
has PubMed identifier	32316118
schema:publication	J Clin Med
resource representing a document's body	covid:a4fdd6a62dce7a973ee523cd8b916abdbaedc1ba#body_text
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