About: Use of Reporter Genes in the Generation of Vaccinia Virus-Derived Vectors

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Use of Reporter Genes in the Generation of Vaccinia Virus-Derived Vectors
Creator	Baldanta, Sara Fernández-Escobar, Mercedes Guerra, Susana Al, Sally
Source	Medline; PMC
abstract	Vaccinia virus (VACV) is one of the most extensively-studied viruses of the Poxviridae family. It is easy to genetically modify, so it has become a key tool for many applications. In this context, reporter genes facilitate the study of the role of foreign genes introduced into the genome of VACV. In this review, we describe the type of reporter genes that have been used to generate reporter-expressing VACV and the applications of the recombinant viruses obtained. Reporter-expressing VACV are currently employed in basic and immunology research, in the development of vaccines and cancer treatment.
has issue date	2016-05-21(xsd:dateTime)
bibo:doi	10.3390/v8050134
bibo:pmid	27213433
has license	cc-by
sha1sum (hex)	a5bfd762a4fb6bdef664818c4e82ca3c718c8862
schema:url	https://doi.org/10.3390/v8050134
resource representing a document's title	Use of Reporter Genes in the Generation of Vaccinia Virus-Derived Vectors
has PubMed Central identifier	PMC4885089
has PubMed identifier	27213433
schema:publication	Viruses
resource representing a document's body	covid:a5bfd762a4fb6bdef664818c4e82ca3c718c8862#body_text
is schema:about of	named entity 'employed' named entity 'REPORTER GENES' named entity 'HAVE' named entity 'IMMUNOLOGY' named entity 'OBTAINED' named entity 'VACCINIA VIRUS' named entity 'KEY' named entity 'VECTORS' named entity 'REVIEW' named entity 'RESEARCH' named entity 'VIRUSES' named entity 'TOOL' named entity 'VACV' named entity 'DESCRIBE' named entity 'MODIFY' named entity 'CURRENTLY EMPLOYED' named entity 'DERIVED' named entity 'GENERATION' named entity 'USE OF' named entity 'RECOMBINANT' named entity 'POXVIRIDAE' named entity 'INTRODUCED INTO' named entity 'APPLICATIONS' named entity 'VACCINIA VIRUS' named entity 'ROLE' named entity 'FOREIGN' named entity 'EASY' named entity 'REPORTER' named entity 'CANCER TREATMENT' named entity 'FAMILY' named entity 'TYPE OF REPORTER' named entity 'USED' named entity 'REPORTER GENES' named entity 'DEVELOPMENT' named entity 'STUDY' named entity 'VACCINES' named entity 'ONE OF' named entity 'CONTEXT' named entity 'VIRUSES' named entity 'GENES' named entity 'BASIC' named entity 'GENERATE' named entity 'GENOME' named entity 'key' named entity 'development' named entity 'genes' named entity 'basic' named entity 'family' named entity 'applications' named entity 'Generation' named entity 'viruses' named entity 'immunology' named entity 'Vaccinia virus' named entity 'vaccines' named entity 'glycosaminoglycans' named entity 'GFP' named entity 'expressed genes' named entity 'virus' named entity 'DNA viruses' named entity 'BrdU' named entity 'symporter' named entity 'cell-mediated immunity' named entity 'radioisotopes' named entity 'expression of the gene' named entity 'Cas9' named entity 'reporter gene' named entity 'nuclear factor' named entity 'viruses' named entity 'BrdU' named entity 'host range' named entity 'oncogenesis' named entity 'gene' named entity 'locus' named entity 'DNA virus' named entity 'retrovirus' named entity 'bacteria' named entity 'type I interferon' named entity 'metabolic'

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