About: Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage
Creator	Liu, Yang Miller, Emily Thakur, Kiran Al-Dalahmah, Osama Canoll, Peter Faust, Phyllis Goldman, James Hargus, Gunnar Hickman, Richard Kunnath-Velayudhan, Shajo Lignelli, Angela Nordvig, Anna Portillo, Armando Prust, Morgan Roth, William Tanji, Kurenai Teich, Andrew Uhlemann, Anne-Catrin
Source	Medline; PMC
abstract	We document the neuropathologic findings of a 73-year old man who died from acute cerebellar hemorrhage in the context of relatively mild SARS-CoV2 infection. The patient developed sudden onset of headache, nausea, and vomiting, immediately followed by loss of consciousness on the day of admission. Emergency medical services found him severely hypoxemic at home, and the patient suffered a cardiac arrest during transport to the emergency department. The emergency team achieved return of spontaneous circulation after over 17 min of resuscitation. A chest radiograph revealed hazy bilateral opacities; and real-time-PCR for SARS-CoV-2 on the nasopharyngeal swab was positive. Computed tomography of the head showed a large right cerebellar hemorrhage, with tonsillar herniation and intraventricular hemorrhage. One day after presentation, he was transitioned to comfort care and died shortly after palliative extubation. Autopsy performed 3 h after death showed cerebellar hemorrhage and acute infarcts in the dorsal pons and medulla. Remarkably, there were microglial nodules and neuronophagia bilaterally in the inferior olives and multifocally in the cerebellar dentate nuclei. This constellation of findings has not been reported thus far in the context of SARS-CoV-2 infection.
has issue date	2020-08-26(xsd:dateTime)
bibo:doi	10.1186/s40478-020-01024-2
bibo:pmid	32847628
has license	cc-by
sha1sum (hex)	a5d7388dace9327f1505c9b3c9c207ad62bf4515
schema:url	https://doi.org/10.1186/s40478-020-01024-2
resource representing a document's title	Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage
has PubMed Central identifier	PMC7447601
has PubMed identifier	32847628
schema:publication	Acta Neuropathol Commun
resource representing a document's body	covid:a5d7388dace9327f1505c9b3c9c207ad62bf4515#body_text
is schema:about of	named entity 'palliative' named entity 'olives' named entity 'microglial' named entity 'Computed tomography' named entity 'cerebellar' named entity 'patient' named entity 'DORSAL PONS' named entity 'RIGHT' named entity 'OLD' named entity 'min' named entity 'consciousness' named entity 'large' named entity 'context' named entity 'This' named entity 'infection' named entity 'neuropathologic' named entity 'hemorrhage' named entity 'patient' named entity 'infarcts' named entity 'hemorrhage' named entity 'SARS-CoV-2' named entity 'cerebellar' named entity 'SARS-CoV-2' named entity 'hemorrhage' named entity 'cerebellar' named entity 'SARS-CoV2' named entity 'cerebellar' named entity 'extubation' named entity 'tonsillar herniation' named entity 'medulla' named entity 'Computed tomography of the head' named entity 'resuscitation' named entity 'Autopsy' named entity 'cardiac arrest' named entity 'cerebellar' named entity 'palliative' named entity 'SARS-CoV-2' named entity 'nodules' named entity 'developed' named entity 'ischemic stroke' named entity 'coagulopathy' named entity 'Hypertensive' named entity 'Histologic examination' named entity 'Emergency medical services' named entity 'cardiac arrest' named entity 'nasopharyngeal swab' named entity 'middle cerebellar peduncle' named entity 'leptomeningeal' named entity 'thrombosis' named entity 'venules' named entity 'tonsillar herniation' named entity 'left lower lobe' named entity 'neurons' named entity 'microglial' named entity 'infarcts' named entity 'dentate nuclei' named entity 'Immunohistochemical staining' named entity 'corpus striatum' named entity 'cytokine' named entity 'CD8' named entity 'SARS-CoV-2' named entity 'white matter' named entity 'inflammation' named entity 'neurons'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software