About: Transmission of Respiratory Syncytial Virus Among Children Under 5 Years in Households of Rural Communities, the Philippines

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About: Transmission of Respiratory Syncytial Virus Among Children Under 5 Years in Households of Rural Communities, the Philippines Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Transmission of Respiratory Syncytial Virus Among Children Under 5 Years in Households of Rural Communities, the Philippines
Creator	Oshitani, Hitoshi Okamoto, Michiko Kamigaki, Taro Lupisan, Socorro Otomaru, Hirono Segubre-Mercado, Edelwisa Tallo, Veronica Tamaki, Raita Alday, Portia Manalo, Joanna Tan, Alvin Oshitani, H Tawat Inobaya, Marianette
Source	PMC
abstract	BACKGROUND: To develop a more effective vaccination strategy for reducing the impact of respiratory syncytial virus (RSV) infection, especially in young infants (<6 months old), it is necessary to understand the transmission dynamics of RSV. METHODS: We conducted a community-based prospective cohort study from 2014 to 2016 in Biliran Province, the Philippines, on children <5 years old. We collected nasopharyngeal swabs from symptomatic children with acute respiratory infection (ARI) during household visits and at health facilities. In households (n = 181) with RSV-positive ARI cases (RSV-ARI), we also identified ARI episodes among other children <5 years old in the same household. In addition, we determined the serial interval to estimate the basic reproduction number (R(0)), the average number of secondary cases generated by a single primary case. RESULTS: In the 181 households analyzed, we found 212 RSV-ARI in 152 households with a single case and 29 households with multiple cases, which included 29 1st RSV-ARI and 31 2nd RSV-ARI. We also found possible index cases among children <5 years old in the same household for 29.0% (18 of 62) of young infants with RSV-ARI. The estimated mean serial interval was 3.2 days, and R(0) was estimated to be 0.92–1.33 for RSV-A and 1.04–1.76 for RSV-B, which varied between different times (2014 and 2015) and places. CONCLUSIONS: Young infants are likely to acquire RSV infection from older children in the same household. Therefore, vaccination targeting older children might protect infants from RSV infection.
has issue date	2019-03-11(xsd:dateTime)
bibo:doi	10.1093/ofid/ofz045
bibo:pmid	30882012
has license	cc-by-nc-nd
sha1sum (hex)	a5f08604ffadbbd3a3759ba8c3b647913bc1c4b6
schema:url	https://doi.org/10.1093/ofid/ofz045
resource representing a document's title	Transmission of Respiratory Syncytial Virus Among Children Under 5 Years in Households of Rural Communities, the Philippines
has PubMed Central identifier	PMC6411217
has PubMed identifier	30882012
schema:publication	Open Forum Infect Dis
resource representing a document's body	covid:a5f08604ffadbbd3a3759ba8c3b647913bc1c4b6#body_text
is schema:about of	named entity 'EFFECTIVE' named entity 'TRANSMISSION' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'STRATEGY' named entity 'INFANTS' named entity 'Households' named entity 'Communities' covid:arg/a5f08604ffadbbd3a3759ba8c3b647913bc1c4b6 named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'DISEASES TRANSMISSION' named entity 'UNDERSTAND' named entity 'CHILDREN' named entity 'OPEN' named entity 'FORUM' named entity 'THE PHILIPPINES' named entity 'HOUSEHOLDS' named entity 'INFECTIOUS DISEASES' named entity 'YOUNG' named entity 'INFECTION' named entity 'YEARS' named entity 'DYNAMICS' named entity 'MONTHS OLD' named entity 'NECESSARY' named entity 'RURAL COMMUNITIES' named entity 'VACCINATION' named entity 'IMPACT' named entity 'RSV' named entity 'REDUCING' named entity 'RSV' named entity 'respiratory syncytial virus (RSV) infection' named entity 'vaccination' named entity 'Respiratory Syncytial Virus' named entity '5 Years' named entity 'RSV infection' named entity 'ARI' named entity 'Biliran' named entity 'infection' named entity 'ARI' named entity 'ARI' named entity 'vaccination' named entity 'ribonucleic acid' named entity 'RSV infection' named entity 'ARI' named entity 'ARI' named entity 'serial interval' named entity 'infection' named entity 'Biliran Province' named entity 'ARI' named entity 'PCR' named entity 'Manila' named entity 'serial interval' named entity 'ARI' named entity 'ARI' named entity 'Maternal antibodies' named entity 'RSV infection' named entity 'ARI' named entity 'ARI' named entity 'infection' named entity 'vaccination' named entity 'ARI' named entity 'antibody' named entity 'transport medium' named entity 'Philippines' named entity 'genotype' named entity 'respiratory syncytial virus' named entity 'serial interval' named entity 'RSV infection' named entity 'coryza' named entity 'ARI'

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