About: Virus-induced pathogenesis, vaccine development, and diagnosis of novel H7N9 avian influenza A virus in humans: a systemic literature review

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Virus-induced pathogenesis, vaccine development, and diagnosis of novel H7N9 avian influenza A virus in humans: a systemic literature review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Virus-induced pathogenesis, vaccine development, and diagnosis of novel H7N9 avian influenza A virus in humans: a systemic literature review
Creator	Assavalapsakul, Wanchai Wang, Sheng-Fan Lin, Chih-Yen Wang, Wen-Hung Thitithanyanont, Arunee Chang Ishcol, Max Erazo, Esmeralda
Source	PMC
abstract	H7N9 avian influenza virus (AIV) caused human infections in 2013 in China. Phylogenetic analyses indicate that H7N9 AIV is a novel reassortant strain with pandemic potential. We conducted a systemic review regarding virus-induced pathogenesis, vaccine development, and diagnosis of H7N9 AIV infection in humans. We followed PRISMA guidelines and searched PubMed, Web of Science, and Google Scholar to identify relevant articles published between January 2013 and December 2018. Pathogenesis data indicated that H7N9 AIV belongs to low pathogenic avian influenza, which is mostly asymptomatic in avian species; however, H7N9 induces high mortality in humans. Sporadic human infections have recently been reported, caused by highly pathogenic avian influenza viruses detected in poultry. H7N9 AIVs resistant to adamantine and oseltamivir cause severe human infection by rapidly inducing progressive acute community-acquired pneumonia, multiorgan dysfunction, and cytokine dysregulation; however, mechanisms via which the virus induces severe syndromes remain unclear. An H7N9 AIV vaccine is lacking; designs under evaluation include synthesized peptide, baculovirus-insect system, and virus-like particle vaccines. Molecular diagnosis of H7N9 AIVs is suggested over conventional assays, for biosafety reasons. Several advanced or modified diagnostic assays are under investigation and development. We summarized virus-induced pathogenesis, vaccine development, and current diagnostic assays in H7N9 AIVs.
has issue date	2019-05-08(xsd:dateTime)
bibo:doi	10.1177/0300060519845488
bibo:pmid	31068040
has license	cc-by-nc
sha1sum (hex)	a699d376b01f2f87cdc9f89e0d0ccdde5c2796a5
schema:url	https://doi.org/10.1177/0300060519845488
resource representing a document's title	Virus-induced pathogenesis, vaccine development, and diagnosis of novel H7N9 avian influenza A virus in humans: a systemic literature review
has PubMed Central identifier	PMC7140199
has PubMed identifier	31068040
schema:publication	J Int Med Res
resource representing a document's body	covid:a699d376b01f2f87cdc9f89e0d0ccdde5c2796a5#body_text
is schema:about of	named entity 'China' named entity 'Special' named entity 'SYSTEMIC' named entity 'DECEMBER' named entity 'OSELTAMIVIR' named entity 'CYTOKINE ' named entity 'CHINA' named entity 'JANUARY' named entity 'ARTICLES' named entity 'STRAIN' named entity 'ACUTE' named entity 'DIAGNOSIS' named entity 'HUMAN' named entity 'SPECIES' named entity 'INDICATED' named entity 'virus' named entity 'human' named entity 'avian influenza' named entity 'oseltamivir' named entity 'potential' named entity 'infection' named entity 'systemic review' named entity 'Web' named entity 'AIV' named entity 'Science' named entity 'infection' named entity 'H7N9' named entity 'inducing' named entity 'virus' named entity 'induces' named entity 'influenza A virus' named entity 'development' named entity 'virus' named entity 'infection' named entity 'systemic review' named entity 'avian influenza virus' named entity 'human' named entity 'influenza A virus' named entity 'monokine induced by gamma interferon' named entity 'antigen' named entity 'adenoviral' named entity 'poultry' named entity 'AIV' named entity 'AS03' named entity 'China' named entity 'viruses' named entity 'immunofluorescence microscopy' named entity 'infection' named entity 'Jiangsu' named entity 'poultry' named entity 'inflammatory responses' named entity 'H7N9' named entity 'genotype' named entity 'clinical trials' named entity 'gold standard' named entity 'epidemic' named entity 'Guangzhou' named entity 'nucleoside' named entity 'baculovirus' named entity 'Baloxavir marboxil' named entity 'genetic reassortment' named entity 'oseltamivir' named entity 'H7N9' named entity 'tissue destruction' named entity 'influenza virus' named entity 'viruses' named entity 'vaccine' named entity 'chicken eggs' named entity 'influenza' named entity 'infection' named entity 'H7N9' named entity 'China' named entity 'United States' named entity 'virus' named entity 'pathogenesis'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software