About: Impact and clinical profiles of Mycoplasma pneumoniae co-detection in childhood community-acquired pneumonia

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About: Impact and clinical profiles of Mycoplasma pneumoniae co-detection in childhood community-acquired pneumonia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Impact and clinical profiles of Mycoplasma pneumoniae co-detection in childhood community-acquired pneumonia
Creator	Zhao, Li Wang, Le Yang, Shuo Fang-Zhou Qiu, Feng, Zhi-Shan Guo, Wei-Wei Li, Gui-Xia Zhao, Meng-Chuan
Source	Medline; PMC
abstract	BACKGROUND: Increasing number of hospitalized children with community acquired pneumonia (CAP) is co-detected with Mycoplasma pneumoniae (Mp). The clinical characteristics and impact of Mp co-detected with other bacterial and/or viral pathogens remain poorly understood. The purpose of this study was to evaluate the demographic and clinical features of CAP children with Mp mono-detection and Mp co-detection. METHODS: A total of 4148 hospitalized children with CAP were recruited from January to December 2017 at the Children’s Hospital of Hebei Province, affiliated to Hebei Medical University. A variety of respiratory viruses, bacteria and Mp were detected using multiple modalities. The demographic and clinical features of CAP children with Mp mono-detection and Mp co-detection were recorded and analyzed. RESULTS: Among the 110 CAP children with Mp positive, 42 (38.18%) of them were co-detected with at least one other pathogen. Co-detection was more common among children aged ≤3 years. No significant differences were found in most clinical symptoms, complications, underlying conditions and disease severity parameters among various etiological groups, with the following exceptions. First, prolonged duration of fever, lack of appetite and runny nose were more prevalent among CAP children with Mp-virus co-detection. Second, Mp-virus (excluding HRV) co-detected patients were more likely to present with prolonged duration of fever. Third, patients co-detected with Mp-bacteria were more likely to have abnormal blood gases. Additionally, CAP children with Mp-HRV co-detection were significantly more likely to report severe runny nose compared to those with Mp mono-detection. CONCLUSION: Mp co-detection with viral and/or bacterial pathogens is common in clinical practice. However, there are no apparent differences between Mp mono-detection and Mp co-detections in terms of clinical features and disease severity.
has issue date	2019-10-11(xsd:dateTime)
bibo:doi	10.1186/s12879-019-4426-0
bibo:pmid	31601192
has license	cc-by
sha1sum (hex)	a74504e83f52c1ed91c0e52adc5af8830d71ae5f
schema:url	https://doi.org/10.1186/s12879-019-4426-0
resource representing a document's title	Impact and clinical profiles of Mycoplasma pneumoniae co-detection in childhood community-acquired pneumonia
has PubMed Central identifier	PMC6788033
has PubMed identifier	31601192
schema:publication	BMC Infect Dis
resource representing a document's body	covid:a74504e83f52c1ed91c0e52adc5af8830d71ae5f#body_text
is schema:about of	named entity 'CAP' named entity 'conditions' named entity 'viruses' named entity 'blood gases' named entity 'features' named entity 'demographic' named entity 'AFFILIATED' named entity 'A43' named entity '110' named entity 'CLINICAL CHARACTERISTICS' named entity 'JANUARY' named entity 'PATHOGEN' named entity 'PRESENT' named entity 'MYCOPLASMA PNEUMONIAE' named entity 'ANALYZED' named entity 'LIKELY' named entity 'CONDITIONS' named entity 'CLINICAL PRACTICE' named entity 'FOUND' named entity 'INCREASING' named entity 'RESULTS' named entity 'DECEMBER' named entity 'FEVER' named entity 'RECORDED' named entity 'DEMOGRAPHIC' named entity 'AGED' named entity 'TERMS' named entity 'CAP' named entity 'BACKGROUND' named entity 'APPARENT' named entity 'EVALUATE' named entity 'COMMON' named entity 'GROUPS' named entity 'HEBEI PROVINCE' named entity 'COMMUNITY ACQUIRED PNEUMONIA' named entity 'IMPACT' named entity 'BACTERIA ' named entity 'VARIETY' named entity 'CLINICAL SYMPTOMS' named entity 'SECOND' named entity 'HAVE' named entity 'VARIOUS' named entity 'CLINICAL FEATURES' named entity 'VIRAL AND' named entity 'MODALITIES' named entity 'SEVERE' named entity 'NUMBER OF' named entity 'DETECTION' named entity 'COMMUNITY-ACQUIRED PNEUMONIA' named entity 'VIRAL PATHOGENS' named entity 'VIRUS' named entity 'REPORT' named entity 'PURPOSE' named entity 'POSITIVE' named entity 'HOSPITAL' named entity 'POORLY' named entity 'CHILDREN' named entity 'PATIENTS' named entity 'MYCOPLASMA PNEUMONIAE' named entity 'DETECTION' named entity 'BACTERIAL PATHOGENS' named entity 'CONCLUSION' named entity 'CLINICAL' named entity 'RUNNY NOSE' named entity '27S' named entity 'LACK OF APPETITE' named entity 'UNDERLYING' named entity 'BACTERIAL' named entity 'COMPLICATIONS' named entity 'UNIVERSITY' named entity 'YEARS' named entity 'RESPIRATORY VIRUSES' named entity 'SIGNIFICANT' named entity 'DETECTED'

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