About: BRAIN MR SPECTROSCOPIC FINDINGS IN THREE CONSECUTIVE COVID-19 PATIENTS: PRELIMINARY OBSERVATIONS

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About: BRAIN MR SPECTROSCOPIC FINDINGS IN THREE CONSECUTIVE COVID-19 PATIENTS: PRELIMINARY OBSERVATIONS Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	BRAIN MR SPECTROSCOPIC FINDINGS IN THREE CONSECUTIVE COVID-19 PATIENTS: PRELIMINARY OBSERVATIONS
Creator	Fischer, David Mukerji, Shibani Schaefer, Pamela Edlow, Brian Eikermann-Haerter, Katharina »more»
source	MedRxiv
abstract	Brain magnetic resonance spectroscopic imaging (MRSI) was performed in three consecutive COVID-19 patients, as part of a pilot investigation of the pathophysiological processes underlying the brain involvement by the SARS-CoV-2 infection. These included one with necrotizing leukoencephalopathy, one after recent PEA cardiac arrest without leukoencephalopathy, and one without frank encephalopathy or recent severe hypoxic episode. The MRSI findings were compared to those of two patients with white matter pathology not SARS-CoV2 infection related, and a control patient without clinical encephalopathy. The N-acetyl-aspartate reduction, choline elevation, and glutamate/glutamine elevation found in the COVID necrotizing leukoencephalopathy patient and, to a lesser degree, the COVID post-cardiac arrest patient, follow a similar pattern as seen with the delayed post-hypoxic leukoencephalopathy patient. Lactate elevation was most pronounced in the patient with COVID necrotizing leukoencephalopathy.
has issue date	2020-06-16(xsd:dateTime)
bibo:doi	10.1101/2020.06.10.20122465
has license	medrxiv
sha1sum (hex)	a96137c1da1510cea3ff8265cb65c392ad28049d
schema:url	https://doi.org/10.1101/2020.06.10.20122465
resource representing a document's title	BRAIN MR SPECTROSCOPIC FINDINGS IN THREE CONSECUTIVE COVID-19 PATIENTS: PRELIMINARY OBSERVATIONS
resource representing a document's body	covid:a96137c1da1510cea3ff8265cb65c392ad28049d#body_text
is schema:about of	named entity 'leukoencephalopathy' named entity 'leukoencephalopathy' named entity 'PAGE' named entity 'DELAYED' named entity 'LACTATE ELEVATION' »more»

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