About: In Vitro Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	In Vitro Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2
Creator	Khaiboullina, Svetlana Verma, Subhash Uppal, Timsy Dhabarde, Nikhil Subramanian, Vaidyanathan
source	BioRxiv
abstract	The newly identified pathogenic human coronavirus, SARS-CoV-2, led to an atypical pneumonia-like severe acute respiratory syndrome (SARS) outbreak called coronavirus disease 2019 (COVID-19). Currently, nearly 23 million cases have been confirmed worldwide with the highest COVID-19 cases been confirmed in the United States. As there is no vaccine or any effective interventions, massive efforts to create a postential vaccine to combat COVID-19 is underway. In the meantime, safety precautions and effective disease control strategies appear to be vital for preventing the virus spread in the public places. Due to the longevity of the virus on smooth surfaces, photocatalytic properties of self-disinfecting/cleaning surfaces appear to be a promising tool to help guide disinfection policies to control infectious SAR-CoV-2 spread in high-traffic areas such as hospitals, grocery stores, airports, schools, and stadiums. Here, we explored the photocatalytic properties of nanosized TiO2 (TNPs) as induced by the UV radiation, towards virus deactivation. Our preliminary results using close genetic relative of SAR-CoV-2, HCoV-NL63, showed the virucidal efficacy of photoactive TNPs deposited on glass coverslips, as examined by quantitative RT-PCR and virus culture assays. Efforts to extrapolate the underlying concepts described in this study to SARS-CoV-2 are currently underway.
has issue date	2020-08-25(xsd:dateTime)
bibo:doi	10.1101/2020.08.25.265223
has license	biorxiv
sha1sum (hex)	a9a62b17f713817ca610e8e92ff8f47e88c051da
schema:url	https://doi.org/10.1101/2020.08.25.265223
resource representing a document's title	In Vitro Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2
schema:publication	bioRxiv
resource representing a document's body	covid:a9a62b17f713817ca610e8e92ff8f47e88c051da#body_text
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