About: Ancient pathogen genomics as an emerging tool for infectious disease research

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Ancient pathogen genomics as an emerging tool for infectious disease research
Creator	Bos, Kirsten Herbig, Alexander Krause, Johannes Spyrou, Maria
Source	Medline; PMC
abstract	Over the past decade, a genomics revolution, made possible through the development of high-throughput sequencing, has triggered considerable progress in the study of ancient DNA, enabling complete genomes of past organisms to be reconstructed. A newly established branch of this field, ancient pathogen genomics, affords an in-depth view of microbial evolution by providing a molecular fossil record for a number of human-associated pathogens. Recent accomplishments include the confident identification of causative agents from past pandemics, the discovery of microbial lineages that are now extinct, the extrapolation of past emergence events on a chronological scale and the characterization of long-term evolutionary history of microorganisms that remain relevant to public health today. In this Review, we discuss methodological advancements, persistent challenges and novel revelations gained through the study of ancient pathogen genomes.
has issue date	2019-04-05(xsd:dateTime)
bibo:doi	10.1038/s41576-019-0119-1
bibo:pmid	30953039
has license	no-cc
sha1sum (hex)	aa779977e2eb9f20709fe36177c984272f8e3927
schema:url	https://doi.org/10.1038/s41576-019-0119-1
resource representing a document's title	Ancient pathogen genomics as an emerging tool for infectious disease research
has PubMed Central identifier	PMC7097038
has PubMed identifier	30953039
schema:publication	Nat Rev Genet
resource representing a document's body	covid:aa779977e2eb9f20709fe36177c984272f8e3927#body_text
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