About: Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis

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About: Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis
Creator	Kennedy, Melissa Ganem, Donald Greenacre, Cheryl Velazquez, Eric Derisi, Joseph Lankton, Julia Ruby, J Stenglein, Mark Wilkes, Rebecca
topic	covid:abb624287a5b93c29ec470b38dd4d03b21c8fc34#this
Source	Medline; PMC
abstract	A colony of domestic rabbits in Tennessee, USA, experienced a high-mortality (~90%) outbreak of enterocolitis. The clinical characteristics were one to six days of lethargy, bloating, and diarrhea, followed by death. Heavy intestinal coccidial load was a consistent finding as was mucoid enteropathy with cecal impaction. Preliminary analysis by electron microscopy revealed the presence of virus-like particles in the stool of one of the affected rabbits. Analysis using the Virochip, a viral detection microarray, suggested the presence of an astrovirus, and follow-up PCR and sequence determination revealed a previously uncharacterized member of that family. Metagenomic sequencing enabled the recovery of the complete viral genome, which contains the characteristic attributes of astrovirus genomes. Attempts to propagate the virus in tissue culture have yet to succeed. Although astroviruses cause gastroenteric disease in other mammals, the pathogenicity of this virus and the relationship to this outbreak remains to be determined. This study therefore defines a viral species and a potential rabbit pathogen.
has issue date	2012-09-22(xsd:dateTime)
bibo:doi	10.1186/1743-422x-9-216
bibo:pmid	22998755
has license	cc-by
sha1sum (hex)	abb624287a5b93c29ec470b38dd4d03b21c8fc34
schema:url	https://doi.org/10.1186/1743-422x-9-216
resource representing a document's title	Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis
has PubMed Central identifier	PMC3502403
has PubMed identifier	22998755
schema:publication	Virol J
resource representing a document's body	covid:abb624287a5b93c29ec470b38dd4d03b21c8fc34#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/abb624287a5b93c29ec470b38dd4d03b21c8fc34
is schema:about of	named entity 'ASTROVIRUSES' named entity 'WAS A' named entity 'RELATIONSHIP' named entity 'VIRAL GENOME' named entity 'VIRUS' named entity 'DIARRHEA' named entity 'PRESENCE OF' named entity 'PCR' named entity 'VIRAL' named entity 'HEAVY' named entity 'IMPACTION' named entity 'INTESTINAL' named entity 'CONTAINS' named entity 'FOLLOW-UP' named entity 'POTENTIAL' named entity 'FAMILY' named entity 'ENTEROPATHY' named entity 'GENOMES' named entity 'ELECTRON MICROSCOPY' named entity 'SEQUENCE' named entity 'SPECIES' named entity 'DISEASE' named entity 'RECOVERY' named entity 'USA' named entity 'tissue culture' named entity 'particles' named entity 'outbreak' named entity 'viral species' named entity 'rabbits' named entity 'pathogenicity' named entity 'gastroenteritis' named entity 'sequence' named entity 'Oryctolagus cuniculus' named entity 'IDENTIFIED' named entity 'GASTROENTERITIS' named entity 'CUNICULUS' named entity 'ANALYSIS' named entity 'ATTRIBUTES' named entity 'AFFECTED' named entity 'FINDING' named entity 'MAMMALS' named entity 'RABBITS' named entity 'VIRAL DETECTION' named entity 'DOMESTIC' named entity 'USING' named entity 'COLONY' named entity 'TISSUE CULTURE' named entity 'HIGH' named entity 'COMPLETE' named entity 'OUTBREAK' named entity 'ONE OF' named entity 'PRESENCE OF VIRUS' named entity 'GENOME SEQUENCE' named entity 'ASTROVIRUS' named entity 'PREVIOUSLY' named entity 'ENABLED' named entity 'FOLLOWED BY' named entity 'MICROARRAY' named entity 'DEATH' named entity 'PRELIMINARY' named entity 'TENNESSEE' named entity 'STUDY' named entity 'DAYS' named entity 'MEMBER OF' named entity 'CECAL' named entity 'CLINICAL CHARACTERISTICS' named entity 'PATHOGEN' named entity '90%' named entity 'EXPERIENCED' named entity 'RABBIT' named entity 'PATHOGENICITY'

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