About: Animal models for dengue vaccine development and testing

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Animal models for dengue vaccine development and testing
Creator	Song, Daesub Choi, Il-Kyu Na, Woonsung Yeom, Minjoo Yook, Heejun Exp, Clin
Source	Medline; PMC
abstract	Dengue fever is a tropical endemic disease; however, because of climate change, it may become a problem in South Korea in the near future. Research on vaccines for dengue fever and outbreak preparedness are currently insufficient. In addition, because there are no appropriate animal models, controversial results from vaccine efficacy assessments and clinical trials have been reported. Therefore, to study the mechanism of dengue fever and test the immunogenicity of vaccines, an appropriate animal model is urgently needed. In addition to mouse models, more suitable models using animals that can be humanized will need to be constructed. In this report, we look at the current status of model animal construction and discuss which models require further development.
has issue date	2017-07-26(xsd:dateTime)
bibo:doi	10.7774/cevr.2017.6.2.104
bibo:pmid	28775974
has license	cc-by-nc
sha1sum (hex)	abd5833ba0f868ce51622b090b9121b3be9c08dc
schema:url	https://doi.org/10.7774/cevr.2017.6.2.104
resource representing a document's title	Animal models for dengue vaccine development and testing
has PubMed Central identifier	PMC5540958
has PubMed identifier	28775974
schema:publication	Clin Exp Vaccine Res
resource representing a document's body	covid:abd5833ba0f868ce51622b090b9121b3be9c08dc#body_text
is schema:about of	named entity 'HAVE' named entity '5B1' named entity 'MORE THAN' named entity 'ANIMAL MODEL' named entity '40%' named entity 'MECHANISM' named entity 'AEDES ALBOPICTUS' named entity 'PEOPLE' named entity 'ENDEMIC DISEASE' named entity 'MILLION' named entity 'ESTIMATED' named entity 'OUTBREAK' named entity 'RESULTS' named entity 'CURRENT' named entity 'ASIA' named entity 'CURRENTLY' named entity 'CENTRAL' named entity 'EXCEPT' named entity 'SOUTH AMERICA' named entity 'CROATIA' named entity 'PROBLEM' named entity 'NEAR' named entity 'ABOUT' named entity 'SELF' named entity 'SINGLE' named entity 'NEED' named entity 'CARGO' named entity 'DENGUE SHOCK SYNDROME' named entity 'SUGGEST' named entity 'ATLANTIC OCEAN' named entity 'SUITABLE' named entity 'PATIENTS' named entity 'RESEARCH' named entity 'ADDITION' named entity 'MOUSE MODELS' named entity 'APPROPRIATE' named entity 'TEST' named entity 'SEROTYPES' named entity 'DSS' named entity 'MODELS' named entity 'INFECTIOUS' named entity 'CAUSES' named entity 'MAJOR' named entity '5B4' named entity 'proper' named entity 'tropics' named entity 'DENV' named entity 'animals' named entity 'A. aegypti' named entity 'needed' named entity 'vaccines' named entity 'serotypes' named entity 'hemorrhagic fever' named entity 'DENGUE' covid:arg/abd5833ba0f868ce51622b090b9121b3be9c08dc named entity 'FUTURE' named entity 'INCREASES' named entity 'INSUFFICIENT' named entity 'CLIMATE CHANGE' named entity 'HUMANIZED' named entity 'PROPER' named entity 'DENGUE HEMORRHAGIC FEVER' named entity 'V A' named entity 'ANIMAL MODELS ' named entity 'THESE' named entity 'INFECTION' named entity 'RNA VIRUS' named entity 'EUROPE' named entity 'IMMUNOGENICITY' named entity 'DIE' named entity 'WORLD' named entity 'PERSONS' named entity 'REPORT' named entity 'CLINICAL TRIALS' named entity 'FAMILY' named entity 'VACCINES'

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