About: Association of Personal Protective Equipment Use with Successful Protection Against COVID-19 Infection Among Health Care Workers

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Association of Personal Protective Equipment Use with Successful Protection Against COVID-19 Infection Among Health Care Workers
Creator	Wang, Wei Weng, Jian-Ping Zhang, Ming Zheng, Xueying Gao, Yong Bao, Wei Bao, Liang, Md Lu, Zhao-Hui Luo, ; Min, Yuan-Zeng Tengchuan, ; Xue, Tian Yang, Chun-Mei
source	MedRxiv
abstract	The coronavirus disease 2019 (COVID-19) pandemic has posed a major challenge for protecting health care workers (HCWs) against the infection. Use of personal protective equipment (PPE) in health care workplace is recommended as a high priority. In order to investigate the relationship between PPE use and the number of COVID-19 cases among HCWs, we conducted a molecular epidemiological study among 142 HCWs who were dispatched from Hefei to work in Wuhan and 284 HCWs who remained in Hefei, China; both provided care for patients with COVID-19. Nucleic acid testing and SARS-CoV-2 specific antibody (IgM, IgG, IgA) detection were performed to confirm SARS-CoV-2 infection among those HCWs. We also extracted publicly released data on daily number of COVID-19 cases among HCWs, daily number of HCWs who were dispatched to Hubei province since January 24, and daily production of PPE in China and daily demand and supply of PPE in Hubei province. Our laboratory testing confirmed that none of the 142 HCWs who were dispatched to work in Wuhan and 284 HCWs who remained in Hefei were infected by SARS-CoV-2. Consistent with these findings, as of April 15, 2020, none of the 42,600 HCWs who were successively dispatched to Hubei province since January 24, 2020 was reported to have COVID-19. These HCWs were provided with adequate supply of PPE as committed by their original institutions or provinces. In contrast, during the early phase of COVID-19 epidemic in Hubei province, a substantial shortage of PPE and an increasing number of COVID-19 infection among HCWs were reported. With the continuing increase in domestic production of PPE in China, the PPE supply started to meet and then exceed the demand. This coincided with a subsequent reduction in the number of reported COVID-19 cases among HCWs. In conclusion, our findings indicate that COVID-19 infection among HCWs could be completely prevented. Appropriate and adequate PPE might play a crucial role in protecting HCWs against COVID-19 infection.
has issue date	2020-04-28(xsd:dateTime)
bibo:doi	10.1101/2020.04.24.20070169
has license	medrxiv
sha1sum (hex)	ac878caa15639228d7e5959db19f1cd854b78639
schema:url	https://doi.org/10.1101/2020.04.24.20070169
resource representing a document's title	Association of Personal Protective Equipment Use with Successful Protection Against COVID-19 Infection Among Health Care Workers
resource representing a document's body	covid:ac878caa15639228d7e5959db19f1cd854b78639#body_text
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