About: Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study

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About: Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study
Creator	Chow, Elaine So, Wing-Yee Kong, Alice Lau, Eric Chanid, Juliana Gogginsid, William Ke Id, Calvin Luk Id, Andrea Maid, Ronald Wu Id, Hongjiang
Source	Medline; PMC
abstract	BACKGROUND: There is very limited data on the time trend of diabetes incidence in Asia. Using population-level data, we report the secular trend of the incidence of type 1 and type 2 diabetes in Hong Kong between 2002 and 2015. METHODS AND FINDINGS: The Hong Kong Diabetes Surveillance Database hosts clinical information on people with diabetes receiving care under the Hong Kong Hospital Authority, a statutory body that governs all public hospitals and clinics. Sex-specific incidence rates were standardised to the age structure of the World Health Organization population. Joinpoint regression analysis was used to describe incidence trends. A total of 562,022 cases of incident diabetes (type 1 diabetes [n = 2,426]: mean age at diagnosis is 32.5 years, 48.4% men; type 2 diabetes [n = 559,596]: mean age at diagnosis is 61.8 years, 51.9% men) were included. Among people aged <20 years, incidence of both type 1 and type 2 diabetes increased. For type 1 diabetes, the incidence increased from 3.5 (95% CI 2.2–4.9) to 5.3 (95% CI 3.4–7.1) per 100,000 person-years (average annual percentage change [AAPC] 3.6% [95% CI 0.2–7.1], p < 0.05) in boys and from 4.3 (95% CI 2.7–5.8) to 6.4 (95% CI 4.3–8.4) per 100,000 person-years (AAPC 4.7% [95% CI 1.7–7.7], p < 0.05] in girls; for type 2 diabetes, the incidence increased from 4.6 (95% CI 3.2–6.0) to 7.5 (95% CI 5.5–9.6) per 100,000 person-years (AAPC 5.9% [95% CI 3.4–8.5], p < 0.05) in boys and from 5.9 (95% CI 4.3–7.6) to 8.5 (95% CI 6.2–10.8) per 100,000 person-years (AAPC 4.8% [95% CI 2.7–7.0], p < 0.05) in girls. In people aged 20 to <40 years, incidence of type 1 diabetes remained stable, but incidence of type 2 diabetes increased over time from 75.4 (95% CI 70.1–80.7) to 110.8 (95% CI 104.1–117.5) per 100,000 person-years (AAPC 4.2% [95% CI 3.1–5.3], p < 0.05) in men and from 45.0 (95% CI 41.4–48.6) to 62.1 (95% CI 57.8–66.3) per 100,000 person-years (AAPC 3.3% [95% CI 2.3–4.2], p < 0.05) in women. In people aged 40 to <60 years, incidence of type 2 diabetes increased until 2011/2012 and then flattened. In people aged ≥60 years, incidence was stable in men and declined in women after 2011. No trend was identified in the incidence of type 1 diabetes in people aged ≥20 years. The present study is limited by its reliance on electronic medical records for identification of people with diabetes, which may result in incomplete capture of diabetes cases. The differentiation of type 1 and type 2 diabetes was based on an algorithm subject to potential misclassification. CONCLUSIONS: There was an increase in incidence of type 2 diabetes in people aged <40 years and stabilisation in people aged ≥40 years. Incidence of type 1 diabetes continued to climb in people aged <20 years but remained constant in other age groups.
has issue date	2020-02-20(xsd:dateTime)
bibo:doi	10.1371/journal.pmed.1003052
bibo:pmid	32078650
has license	cc-by
sha1sum (hex)	acdc7132a3cc967450623c8ddcb38ec4214f6850
schema:url	https://doi.org/10.1371/journal.pmed.1003052
resource representing a document's title	Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study
has PubMed Central identifier	PMC7032690
has PubMed identifier	32078650
schema:publication	PLoS Med
resource representing a document's body	covid:acdc7132a3cc967450623c8ddcb38ec4214f6850#body_text
is schema:about of	named entity 'TYPE 1' named entity '2002' named entity 'DATA' named entity 'REPORT' named entity '2015' named entity 'TREND' named entity 'USING' named entity 'HONG KONG' named entity 'HONG KONG' named entity 'TYPE 1' named entity 'RETROSPECTIVE COHORT STUDY' named entity 'INCIDENCE' named entity 'SECULAR TRENDS' named entity 'INCIDENCE' named entity 'TYPE 2 DIABETES' named entity 'SECULAR TREND' named entity 'ASIA' named entity 'DIABETES INCIDENCE' named entity 'TYPE 2 DIABETES' named entity 'TIME' named entity 'VERY LIMITED' named entity 'data' named entity 'type 2 diabetes' named entity 'retrospective cohort study' named entity 'type 2 diabetes' named entity 'diabetes' named entity 'type 1' named entity 'Asia' named entity 'secular trend' named entity 'drug prescriptions' named entity 'Hong Kong' named entity 'Korea' named entity 'diabetes' named entity 'nutrition' named entity 'diabetic ketoacidosis' named entity 'Asian' named entity 'health policy makers' named entity 'Hong Kong' named entity 'aetiologies' named entity 'Bethesda, MD' named entity '95% CI' named entity 'incidence rates' named entity 'type 1' named entity 'type 2 diabetes' named entity 'gestational diabetes' named entity '400 million' named entity 'primary care' named entity 'age structure' named entity 'data set' named entity 'NPV' named entity 'metabolic complications' named entity 'disease burden' named entity 'incidence rates' named entity 'diabetes' named entity 'Hong Kong' named entity 'cubic spline' named entity 'type 1 diabetes' named entity '95% CI' named entity 'type 2 diabetes' named entity 'world's population' named entity 'type 2 diabetes' named entity 'autoimmune' named entity 'cubic spline' named entity 'autoantibodies' named entity '95% CI' named entity 'Diabetes' named entity 'type 2 diabetes' named entity 'HbA1c' named entity 'insulin' named entity 'type 1 diabetes' named entity 'type 1 diabetes' named entity 'type 1 diabetes'

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