About: UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings
Creator	Touyz, Rhian Kehoe, Patrick O'sullivan, Michael Aimable, Margaux Allan, Stuart Bath, Philip Bernard, Ashton Brezzo, Gaia Carare, Roxana Carswell, Hilary Clarkson, Andrew Currie, Gillian Farr, Tracy Fowler, Jill Good, Mark Hainsworth, Atticus Hall, Catherine Hietamies, Tuuli Horsburgh, Karen Kalaria, Rajesh Lawrence, Catherine Macleod, Malcolm Miller, Alyson Miners, Scott Mok, Vincent Platt, Bettina Quinn, Terence Sena, Emily Sharp, Matthew Strangward, Patrick Szymkowiak, Stefan Trueman, Rebecca White, Claire Work, Lorraine Mccabe, Chris Mccoll, Barry Mcfall, Aisling Mcneilly, Alison
Source	PMC
abstract	Assessment of outcome in preclinical studies of vascular cognitive impairment (VCI) is heterogenous. Through an ARUK Scottish Network supported questionnaire and workshop (mostly UK-based researchers), we aimed to determine underlying variability and what could be implemented to overcome identified challenges. Twelve UK VCI research centres were identified and invited to complete a questionnaire and attend a one-day workshop. Questionnaire responses demonstrated agreement that outcome assessments in VCI preclinical research vary by group and even those common across groups, may be performed differently. From the workshop, six themes were discussed: issues with preclinical models, reasons for choosing functional assessments, issues in interpretation of functional assessments, describing and reporting functional outcome assessments, sharing resources and expertise, and standardization of outcomes. Eight consensus points emerged demonstrating broadly that the chosen assessment should reflect the deficit being measured, and therefore that one assessment does not suit all models; guidance/standardisation on recording VCI outcome reporting is needed and that uniformity would be aided by a platform to share expertise, material, protocols and procedures thus reducing heterogeneity and so increasing potential for collaboration, comparison and replication. As a result of the workshop, UK wide consensus statements were agreed and future priorities for preclinical research identified.
has issue date	2020-03-09(xsd:dateTime)
bibo:doi	10.1177/0271678x20910552
bibo:pmid	32151228
has license	cc-by
sha1sum (hex)	ad6dcaac5049ab3a13720708ec39d7ab18801a00
schema:url	https://doi.org/10.1177/0271678x20910552
resource representing a document's title	UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings
has PubMed Central identifier	PMC7307003
has PubMed identifier	32151228
schema:publication	J Cereb Blood Flow Metab
resource representing a document's body	covid:ad6dcaac5049ab3a13720708ec39d7ab18801a00#body_text
is schema:about of	named entity 'VCI' named entity 'uniformity' named entity 'Assessment' named entity 'heterogeneity' named entity 'share' named entity 'determine' named entity 'WHAT' named entity 'COMPARISON' named entity 'SHARE' named entity 'HETEROGENOUS' named entity 'SHARING' named entity 'CHOOSING' named entity 'GROUPS' named entity 'UNDERLYING' named entity 'OUTCOME' named entity 'MATERIAL' named entity 'RESEARCHERS' named entity 'MEASURED' named entity 'PERFORMED' named entity 'POTENTIAL' named entity 'DESCRIBING' named entity 'VASCULAR COGNITIVE IMPAIRMENT' named entity 'REPORTING' named entity 'SUPPORTED' named entity 'AGREEMENT' named entity 'collaboration' named entity 'VCI' named entity 'preclinical' named entity 'demonstrating' named entity 'performed' named entity 'UK-based' named entity 'Network' named entity 'aided' named entity 'Eight' named entity 'assessments' named entity 'vascular cognitive impairment' named entity 'preclinical studies' named entity 'proceedings' named entity 'preclinical research' named entity 'VCI' named entity 'questionnaire' named entity 'preclinical research' named entity 'preclinical models' named entity 'vascular cognitive impairment'

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