About: A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe
Creator	Hernán, Miguel Reinoso-Barbero, Francisco Arribas, José Arnalich, Francisco Arribas, Daniel Borobia, Alberto Buño, Antonio Carcas, Antonio Concepción Núñez, M Cuevas, Esther Figueira, Juan Frías, Jesús García-Arenzana, Nicolás García-Rodríguez, Julio Martin-Quiros, Alejandro Martí-De-Gracia, Milagros Martín-Vega, Alberto Martínez-Alés, Gonzalo Mingorance, Jesús Monserrat-Villatoro, Jaime Prados Sánchez, Concepción Quintana, Manuel Ramos, Francisco Ramírez, Elena Rios, Juan Rivera Núñez, Angélica Segura, Carlos Torres Santos-Olmo, Rosario
Source	Medline; PMC; WHO
abstract	Background: Since the confirmation of the first patient infected with SARS-CoV-2 in Spain in January 2020, the epidemic has grown rapidly, with the greatest impact on the region of Madrid. This article describes the first 2226 adult patients with COVID-19, consecutively admitted to La Paz University Hospital in Madrid. Methods: Our cohort included all patients consecutively hospitalized who had a final outcome (death or discharge) in a 1286-bed hospital of Madrid (Spain) from 25 February (first case admitted) to 19 April 2020. The data were manually entered into an electronic case report form, which was monitored prior to the analysis. Results: We consecutively included 2226 adult patients admitted to the hospital who either died (460) or were discharged (1766). The patients’ median age was 61 years, and 51.8% were women. The most common comorbidity was arterial hypertension (41.3%), and the most common symptom on admission was fever (71.2%). The median time from disease onset to hospital admission was 6 days. The overall mortality was 20.7% and was higher in men (26.6% vs. 15.1%). Seventy-five patients with a final outcome were transferred to the intensive care unit (ICU) (3.4%). Most patients admitted to the ICU were men, and the median age was 64 years. Baseline laboratory values on admission were consistent with an impaired immune-inflammatory profile. Conclusions: We provide a description of the first large cohort of hospitalized patients with COVID-19 in Europe. Advanced age, male sex, the presence of comorbidities and abnormal laboratory values were more common among the patients with fatal outcomes.
has issue date	2020-06-04(xsd:dateTime)
bibo:doi	10.3390/jcm9061733
bibo:pmid	32512688
has license	cc-by
sha1sum (hex)	af09ed2dc0b2efe8c1d80de44b67023cfae5616d
schema:url	https://doi.org/10.3390/jcm9061733
resource representing a document's title	A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe
has PubMed Central identifier	PMC7356883
has PubMed identifier	32512688
schema:publication	J Clin Med
resource representing a document's body	covid:af09ed2dc0b2efe8c1d80de44b67023cfae5616d#body_text
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