Subgroup analyses showed among the general population , ACEI / ARB therapy was associated with reduced severe COVID - 19 infection ( OR : 0 . 79 , 95 % CI : 0 . 60 - 1 . 05 ) and all - cause mortality ( OR : 0 . 31 , 95 % CI : 0 . 13 - 0 . 75 ) , and COVID - 19 infection (