The median duration of symptoms for participants receiving placebo was 116 · 7 h ( 95 % CI 108 · 1 - 122 · 1 ) compared with 95 · 5 h ( 84 · 0 - 108 · 0 ; p = 0 · 0084 ) for those receiving 600 mg nitazoxanide and 109 · 1 h ( 96 · 1 - 129 · 5 , p = 0 · 52 )