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  • Thus , there was no proliferation and only moderate IFN - y production in response to peptide , but in contrast , a significant and early peptide - induced IL - 4 and TGF - f3 response was observed . The data suggest that the MHC - associated susceptibility to EAE is partly related to the ability to mount a TH1 - like immune response while the MHC - associated EAE resistance may
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