Regarding adverse events , glucocorticoids use was not associated with an increased risk for nosocomial infections ( RR 0 . 82 ; 95 % CI 0 . 68 - 1 . 00 ; P = 0 . 05 ) ; however , it was associated with an increased risk of hyperglycemia ( RR 1 . 11 ; 95 % CI 1 . 01 - 1 . 24 ; P = 0 . 04 )