Although not confirmed in all studies with a symmetric distribution of the 23 confounding factors investigated , the overall analyses showed that there was a relationship between childhood viral LRTI at < 5 years and serum test diagnosed - atopy ( OR = 2 . 0 , [ 95 % CI = 1 . 0 - 4 . 1 ] ) , allergic rhinoconjunctivitis ( OR = 1 . 7 ,