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  • Together , circulating ACE2 levels , but not Ang - ( 1 - 7 ) and Ang - ( 1 - 9 ) levels , significantly increased in female CHD group when compared with non - CHD group , increased ACE2 was independently associated with CHD in female and in patients with multi - vessel lesions even after adjusting for the confounding factors , indicating that ACE2 may participate as a compensatory mechanism in CHD
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