About: Effect of in ovo bursectomy on the course of an infectious bronchitis virus infection in line C White Leghorn chickens

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About: Effect of in ovo bursectomy on the course of an infectious bronchitis virus infection in line C White Leghorn chickens Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effect of in ovo bursectomy on the course of an infectious bronchitis virus infection in line C White Leghorn chickens
Creator	Cook, J Davison, T Huggins, M Mclaughlan, P
Source	PMC
abstract	White Leghorn line C chicks were surgically bursectomised (Bx) in ovo to eliminate antibody production. After inoculation with infectious bronchitis virus (IBV) at 14 days after hatching, Bx chicks experienced a more severe and longer lasting infection than intact chicks. The severity and duration of clinical infection in the Bx chicks resembled that previously observed in the highly susceptible line 15 I chicks, however no increase in mortality was observed, in contrast to the high levels of mortality recorded in IBV-inoculated line 15 I chicks. After secondary challenge the degree of damage to the ciliated epithelium of the trachea was greater in the Bx chicks than in the intact chicks. The results indicate that, although antibodies play an important role in recovery from IBV infection, other immunological factor(s) may also be involved.
has issue date	1991-01-01(xsd:dateTime)
bibo:doi	10.1007/bf01314032
bibo:pmid	1648896
has license	no-cc
sha1sum (hex)	b138a86cef4262e1cc6049caa977053c17136018
schema:url	https://doi.org/10.1007/bf01314032
resource representing a document's title	Effect of in ovo bursectomy on the course of an infectious bronchitis virus infection in line C White Leghorn chickens
has PubMed Central identifier	PMC7087224
has PubMed identifier	1648896
schema:publication	Arch Virol
resource representing a document's body	covid:b138a86cef4262e1cc6049caa977053c17136018#body_text
is schema:about of	named entity 'observed' named entity 'secondary' named entity 'experienced' named entity 'White Leghorn' named entity 'COURSE' named entity 'DURATION' named entity 'CONTRAST' named entity 'OBSERVED' named entity 'HATCHING' named entity 'INCREASE' named entity 'CLINICAL INFECTION' named entity 'EXPERIENCED' named entity 'SEVERE' named entity 'CHALLENGE' named entity 'LEVELS' named entity 'ANTIBODY PRODUCTION' covid:arg/b138a86cef4262e1cc6049caa977053c17136018 named entity 'HIGH' named entity 'SECONDARY' named entity 'WHITE LEGHORN' named entity 'TRACHEA' named entity 'PREVIOUSLY' named entity 'CHICKS' named entity 'DEGREE' named entity 'LINE' named entity 'LINE' named entity 'INFECTIOUS BRONCHITIS VIRUS' named entity 'INFECTIOUS BRONCHITIS VIRUS' named entity 'EFFECT' named entity 'VIRUS INFECTION' named entity 'CHICKENS' named entity 'DAMAGE' named entity 'SUSCEPTIBLE' named entity 'SURGICALLY' named entity 'CILIATED EPITHELIUM' named entity 'INTACT' named entity 'INFECTION' named entity 'GREATER' named entity 'IN OVO' named entity 'BURSECTOMY' named entity 'WHITE LEGHORN' named entity 'IN OVO' named entity 'MORTALITY' named entity 'DAYS' named entity 'RECORDED' named entity 'HIGHLY' named entity 'INOCULATION' named entity 'SEVERITY' named entity 'surgically' named entity 'mortality' named entity 'mortality' named entity 'epithelium' named entity 'infection' named entity 'trachea' named entity 'infection' named entity 'IBV' named entity 'IBV' named entity 'CMI' named entity 'penicillin' named entity 'inoculation' named entity 'antibody' named entity 'IgG antibodies' named entity 'Trachea' named entity 'IBV' named entity 'inocula' named entity 'IBV' named entity 'cell-mediated immune responses' named entity 'inoculation' named entity 'epithelium' named entity 'homogenised' named entity 'virus' named entity 'upper respiratory tract' named entity 'IBV' named entity 'B-system' named entity 'antibodies' named entity 'lungs' named entity 'IBV' named entity 'antibody'

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