About: COVID-19 associated kidney impairment in adult: qualitative and quantitative analyses with non-enhanced CT on admission

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About: COVID-19 associated kidney impairment in adult: qualitative and quantitative analyses with non-enhanced CT on admission Goto Sponge NotDistinct Permalink

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 associated kidney impairment in adult: qualitative and quantitative analyses with non-enhanced CT on admission
Creator	Chen, Feng Yang, Rong Li, Jian Liang, Wenjie Liu, Jinpeng Zhang, Rui Huang, Qiang Li, Huang Lyu, Shuangzhi Xiao, Wenbo Yan, Senxiang Zheng, Liangrong Huang, # Liang, Lyu
Source	Elsevier; PMC
abstract	PURPOSE: To qualitatively and quantitatively assess kidney imapairment in adults with COVID-19 by analysing imaging features on non-enhanced CT (NECT) and possible correlation between renal parenchymal attenuation (RPA) and serum creatinine (SCr) levels on admission. METHODS: This study was approved by the local institutional ethics committee. A total of 82 patients with COVID-19 admitted from 10/1/2020∼15/3/2020 were enrolled. RPA and perinephric fat stranding (PFS) were evaluated on NECT imaging. According to the presence of PFS, the patients were divided into two groups: Group A, 38 patients with PFS, and Group B, 44 patients without PFS. Clinical data, including age, gender, clinical classification, SCr levels, and RPA on NECT were analysed. The RPA and SCr of the two groups with COVID-19 were analysed to determine possible difference and correlation. Eighty subjects with no kidney diseases were randomly selected as control group to determine the RPA of normal kidney performed on the same CT scanner. RESULTS: Mean age, male to female ratio, number of severe and critical cases, and SCr of Group A were higher than those of Group B. Both mean RPA of Group A and Group B were lower than that of control. Mean RPA of Group A was even lower than that of Group B. A significant weak negative linear correlation between RPA on NECT and SCr in COVID-19 was indicated. CONCLUSIONS: Decrease in RPA on NECT was observed in patients with COVID-19 and a weak linear negative correlation with SCr levels was found. The presence of PFS suggested more severe renal impairment in COVID-19. RPA measurements and PFS could be useful in quantitative and qualitative evaluation of COVID-19 associated renal impairment on admission.
has issue date	2020-08-26(xsd:dateTime)
bibo:doi	10.1016/j.ejrad.2020.109240
has license	no-cc
sha1sum (hex)	b1e1c26d8ef5438deeefedc31f397422736ec9f9
schema:url	https://doi.org/10.1016/j.ejrad.2020.109240
resource representing a document's title	COVID-19 associated kidney impairment in adult: qualitative and quantitative analyses with non-enhanced CT on admission
has PubMed Central identifier	PMC7448815
schema:publication	Eur J Radiol
resource representing a document's body	covid:b1e1c26d8ef5438deeefedc31f397422736ec9f9#body_text
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