About: Effect of acute respiratory infections in infancy on pulmonary function test at 3 years of age: a prospective birth cohort study

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About: Effect of acute respiratory infections in infancy on pulmonary function test at 3 years of age: a prospective birth cohort study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effect of acute respiratory infections in infancy on pulmonary function test at 3 years of age: a prospective birth cohort study
Creator	Lodha, Rakesh Kapil, Arti Kumar, Prawin Mukherjee, Aparna Randev, Shivani Medigeshi, Guruprasad Jat, Kana Kabra, Kumar Kabra, Sushil Sushil, Dr
Source	Medline; PMC
abstract	INTRODUCTION: Acute respiratory infections (ARIs) in infancy may have a long-term impact on the developing respiratory system. We planned a prospective cohort study to determine the impact of ARI during infancy on the pulmonary function test indices at 3 years of age. METHODS: A cohort of normal, full-term newborns were followed up 6 monthly and during ARI episodes. Infant pulmonary function tests (IPFTs) were performed at baseline and each follow-up visit using tidal breathing flow-volume loop, rapid thoracoabdominal compression (RTC) and raised volume RTC manoeuvres. During each ARI episode, nasopharyngeal aspirates were tested for respiratory pathogens by real-time PCR. RESULTS: We screened 3421 neonates; 310 were enrolled; IPFT was performed in 225 (boys: 125 (55.6%)) at 3 years. During infancy, 470 ARI episodes were documented in 173 infants. At 3 years, children with history of any ARI episode during infancy had lower forced expiratory volume in 1 s (FEV(1.0)), forced expiratory volume in 0.75 s (FEV(0.75)), forced expiratory volume in 0.5 s (FEV(0.5)), forced expiratory flow between 25% and 75% of FVC (FEF(25–75)), and maximal expiratory flow at 25% of FVC (MEF(25)) as compared with those without any ARI episode during infancy. The ratio of tidal expiratory flow (TEF) at 25% or 50% of tidal expiratory volume to peak TEF (TEF(50) or TEF(25)/peak TEF) at 3 years was significantly increased in children who had ARI in infancy. CONCLUSIONS: ARI during infancy is associated with impaired pulmonary function indices such as increased resistance and decreased forced expiratory flow and volume at 3 years of age.
has issue date	2020-02-19(xsd:dateTime)
bibo:doi	10.1136/bmjresp-2019-000436
bibo:pmid	32079606
has license	cc-by-nc
sha1sum (hex)	b399adcfb1d563f2c836e2c924fb0c090fca961a
schema:url	https://doi.org/10.1136/bmjresp-2019-000436
resource representing a document's title	Effect of acute respiratory infections in infancy on pulmonary function test at 3 years of age: a prospective birth cohort study
has PubMed Central identifier	PMC7047475
has PubMed identifier	32079606
schema:publication	BMJ Open Respir Res
resource representing a document's body	covid:b399adcfb1d563f2c836e2c924fb0c090fca961a#body_text
is schema:about of	named entity 'LUNG DISEASE' named entity 'THEIR' named entity 'INCREASED RESISTANCE' named entity 'INFLUENCE' named entity 'BIRTH COHORT STUDY' named entity 'ONE OF' named entity 'IMPAIRMENT' named entity 'infant' named entity 'resistance' named entity 'BIRTH COHORT STUDY' covid:arg/b399adcfb1d563f2c836e2c924fb0c090fca961a named entity 'HIGHER' named entity 'ACUTE RESPIRATORY INFECTIONS' named entity 'REFLECTING' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'LIMITATION' named entity 'PROSPECTIVE' named entity 'YEARS' named entity 'INFANCY' named entity 'INFANT' named entity 'PULMONARY FUNCTION TEST' named entity 'INFECTIONS' named entity 'COHORT STUDIES' named entity 'INFANCY' named entity 'BIRTH COHORT' named entity 'APART' named entity 'DOCUMENTED' named entity 'AIRWAY RESISTANCE' named entity 'FLOW' named entity 'ASSOCIATION' named entity 'PULMONARY FUNCTION TEST' named entity 'ASSOCIATED WITH' named entity 'FLOW RATE' named entity 'INDICATED' named entity 'AGE' named entity 'RHINOVIRUS' named entity 'AGE' named entity 'PAEDIATRIC' named entity 'EFFECT' named entity 'FORCED EXPIRATORY VOLUME' named entity 'PROSPECTIVE' named entity 'INDICES' named entity 'IMPAIRED' named entity '27S' named entity 'AETIOLOGY' named entity 'ASIA' named entity 'DEMONSTRATED' named entity 'HUMAN METAPNEUMOVIRUS' named entity 'YEARS' named entity 'HUMAN CORONAVIRUS' named entity 'LOWER' named entity 'ARI' named entity 'indices' named entity 'human metapneumovirus' named entity 'airway resistance' named entity 'influence' named entity 'prospective' named entity 'This' named entity 'pulmonary function test' named entity 'rhinovirus' named entity 'years of age' named entity 'Paediatric' named entity 'cohort study' named entity 'respiratory infections' named entity 'lung disease' named entity 'breast feeding' named entity 'IPFT' named entity 'pulmonary function test' named entity 'pathogens' named entity 'Finland' named entity 'FEV' named entity 'India'

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