About: Probiotics and Paraprobiotics in Viral Infection: Clinical Application and Effects on the Innate and Acquired Immune Systems

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About: Probiotics and Paraprobiotics in Viral Infection: Clinical Application and Effects on the Innate and Acquired Immune Systems Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Probiotics and Paraprobiotics in Viral Infection: Clinical Application and Effects on the Innate and Acquired Immune Systems
Creator	Yamamoto, Naoki Andoh, Akira Kanauchi, Osamu Abubakar, Sazaly
Source	Medline; PMC
abstract	Recently, the risk of viral infection has dramatically increased owing to changes in human ecology such as global warming and an increased geographical movement of people and goods. Howev-er, the efficacy of vaccines and remedies for infectious diseases is limited by the high mutation rates of viruses, especially, RNA viruses. Here, we comprehensively review the effectiveness of several probiot-ics and paraprobiotics (sterilized probiotics) for the prevention or treatment of virally-induced infectious diseases. We discuss the unique roles of these agents in modulating the cross-talk between commensal bacteria and the mucosal immune system. In addition, we provide an overview of the unique mechanism by which viruses are eliminated through the stimulation of type 1 interferon production by probiotics and paraprobiotics via the activation of dendritic cells. Although further detailed research is necessary in the future, probiotics and/or paraprobiotics are expected to be among the rational adjunctive options for the treatment of various viral diseases.
has issue date	2018-02-01(xsd:dateTime)
bibo:doi	10.2174/1381612824666180116163411
bibo:pmid	29345577
has license	cc-by-nc
sha1sum (hex)	b3c7cd5491836d0e345797bad2673c79ceaffe67
schema:url	https://doi.org/10.2174/1381612824666180116163411
resource representing a document's title	Probiotics and Paraprobiotics in Viral Infection: Clinical Application and Effects on the Innate and Acquired Immune Systems
has PubMed Central identifier	PMC6006794
has PubMed identifier	29345577
schema:publication	Curr Pharm Des
resource representing a document's body	covid:b3c7cd5491836d0e345797bad2673c79ceaffe67#body_text
is schema:about of	named entity 'ADDITION' named entity 'EFFICACY' named entity 'ROLES' named entity 'MODULATING' named entity 'MUTATION RATES' named entity 'NECESSARY' named entity 'OPTIONS' named entity 'INFECTIOUS DISEASES' named entity 'STIMULATION' named entity 'MOVEMENT' named entity 'ELIMINATED' named entity 'THESE' named entity 'RNA VIRUSES' named entity 'VIRAL INFECTION' named entity 'DENDRITIC CELLS' named entity 'PREVENTION' named entity 'GLOBAL WARMING' named entity 'VACCINES' named entity 'VIRUSES' named entity 'REVIEW' named entity 'INDUCED' named entity 'MUCOSAL IMMUNE SYSTEM' named entity 'CURRENT' named entity 'DESIGN' named entity 'FACTOR' named entity 'IMPACT' named entity 'BACTERIA ' named entity 'ADJUNCTIVE' named entity 'EXPECTED' named entity 'EFFECTIVENESS' named entity 'LIMITED BY' named entity 'PROVIDE' named entity 'TYPE 1' named entity 'ACTIVATION' named entity 'HIGH' named entity 'VIRAL DISEASES' named entity 'PEOPLE' named entity 'RECENTLY' named entity 'MECHANISM' named entity 'DETAILED' named entity 'HUMAN ECOLOGY' named entity 'RESEARCH' named entity 'RISK OF' named entity 'GEOGRAPHICAL' named entity 'INCREASED' named entity 'HERE' named entity 'FUTURE' named entity 'PHARMACEUTICAL' named entity 'UNIQUE' named entity 'OVERVIEW' named entity 'GOODS' named entity 'INTERFERON PRODUCTION' named entity 'DISCUSS' named entity 'COMMENSAL BACTERIA' named entity 'PROBIOTICS' named entity 'TREATMENT' named entity 'VARIOUS' named entity 'CHANGES' named entity 'CROSS-TALK' named entity 'global warming' named entity 'infectious diseases' named entity 'mucosal' named entity 'viral diseases' named entity 'commensal bacteria' named entity 'infectious diseases' named entity 'probiotics' named entity 'ligands' named entity 'first-line' named entity 'influenza virus' named entity 'peripheral blood mononuclear cells' named entity 'RNA-dependent RNA polymerase' named entity 'L. lactis' named entity 'probiotic' named entity 'IFN' named entity 'virus' named entity 'type 1 IFN' named entity 'NK cells' named entity 'rotavirus'

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