About: Evaluation of NxTAG Respiratory Pathogen Panel and Comparison with xTAG Respiratory Viral Panel Fast v2 and Film Array Respiratory Panel for Detecting Respiratory Pathogens in Nasopharyngeal Aspirates and Swine/Avian-Origin Influenza A Subtypes in Culture Isolates

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About: Evaluation of NxTAG Respiratory Pathogen Panel and Comparison with xTAG Respiratory Viral Panel Fast v2 and Film Array Respiratory Panel for Detecting Respiratory Pathogens in Nasopharyngeal Aspirates and Swine/Avian-Origin Influenza A Subtypes in Culture Isolates Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Evaluation of NxTAG Respiratory Pathogen Panel and Comparison with xTAG Respiratory Viral Panel Fast v2 and Film Array Respiratory Panel for Detecting Respiratory Pathogens in Nasopharyngeal Aspirates and Swine/Avian-Origin Influenza A Subtypes in Culture Isolates
Creator	Chen, H Li, P Yuen, K Chan, J Chan, K Hung, I Wong, T Chan, G Chik, K Hk, K To, K Yip, C Yuen, Zhang, R
topic	covid:b4625acf19fca7b49e058b46f640125fa4e367f5#this
source	Medline; PMC
abstract	This study evaluated a new multiplex kit, Luminex NxTAG Respiratory Pathogen Panel, for respiratory pathogens and compared it with xTAG RVP Fast v2 and FilmArray Respiratory Panel using nasopharyngeal aspirate specimens and culture isolates of different swine/avian-origin influenza A subtypes (H2N2, H5N1, H7N9, H5N6, and H9N2). NxTAG RPP gave sensitivity of 95.2%, specificity of 99.6%, PPV of 93.5%, and NPV of 99.7%. NxTAG RPP, xTAG RVP, and FilmArray RP had highly concordant performance among each other for the detection of respiratory pathogens. The mean analytic sensitivity (TCID50/ml) of NxTAG RPP, xTAG RVP, and FilmArray RP for detection of swine/avian-origin influenza A subtype isolates was 0.7, 41.8, and 0.8, respectively. All three multiplex assays correctly typed and genotyped the influenza viruses, except for NxTAG RRP that could not distinguish H3N2 from H3N2v. Further investigation should be performed if H3N2v is suspected to be the cause of disease. Sensitive and specific laboratory diagnosis of all influenza A viruses subtypes is especially essential in certain epidemic regions, such as Southeast Asia. The results of this study should help clinical laboratory professionals to be aware of the different performances of commercially available molecular multiplex RT-PCR assays that are commonly adopted in many clinical diagnostic laboratories.
has issue date	2017-08-29(xsd:dateTime)
bibo:doi	10.1155/2017/1324276
bibo:pmid	28947901
has license	cc-by
sha1sum (hex)	b4625acf19fca7b49e058b46f640125fa4e367f5
schema:url	https://doi.org/10.1155/2017/1324276
resource representing a document's title	Evaluation of NxTAG Respiratory Pathogen Panel and Comparison with xTAG Respiratory Viral Panel Fast v2 and Film Array Respiratory Panel for Detecting Respiratory Pathogens in Nasopharyngeal Aspirates and Swine/Avian-Origin Influenza A Subtypes in Culture Isolates
has PubMed Central identifier	PMC5602486
has PubMed identifier	28947901
schema:publication	Adv Virol
resource representing a document's body	covid:b4625acf19fca7b49e058b46f640125fa4e367f5#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/b4625acf19fca7b49e058b46f640125fa4e367f5
is schema:about of	named entity 'FAST' named entity 'ASPIRATES' named entity 'isolates' named entity 'Pathogens' named entity 'DETECTING' named entity 'RESPIRATORY' named entity 'PERFORMANCE' named entity 'RVP' named entity 'MULTIPLEX' named entity 'SENSITIVE' named entity 'RESPIRATORY PATHOGEN PANEL' named entity 'EVALUATION' named entity 'PANEL' named entity 'CULTURE' named entity 'H3N2' named entity 'INVESTIGATION' covid:arg/b4625acf19fca7b49e058b46f640125fa4e367f5 named entity 'PANEL' named entity 'DETECTION' named entity 'H7N9' named entity 'STUDY' named entity 'REGIONS' named entity 'RESPIRATORY PATHOGEN PANEL' named entity 'LABORATORY DIAGNOSIS' named entity 'H5N1' named entity 'ORIGIN' named entity 'ARRAY' named entity 'CERTAIN' named entity 'ORIGIN' named entity 'ISOLATES' named entity 'EPIDEMIC' named entity 'SUBTYPES' named entity 'HIGHLY' named entity 'RESPIRATORY VIRAL PANEL' named entity 'ISOLATES' named entity 'COMPARISON' named entity 'NASOPHARYNGEAL' named entity 'SUBTYPES' named entity 'RESPIRATORY' named entity 'RESPIRATORY PATHOGENS' named entity 'PPV' named entity 'CONCORDANT' named entity 'SPECIFIC' named entity 'EVALUATED' named entity 'SENSITIVITY' named entity 'COMPARED' named entity 'LUMINEX' named entity 'SWINE' named entity '0.8' named entity 'USING' named entity 'SPECIFICITY' named entity 'DISEASE' named entity 'FAST' named entity 'RRP' named entity 'SOUTHEAST ASIA' named entity 'SPECIMENS' named entity 'RESPIRATORY PATHOGENS' named entity 'SUBTYPE' named entity 'KIT' named entity 'EXCEPT FOR' named entity 'PERFORMED' named entity '0.7' named entity 'DIFFERENT' named entity 'GAVE' named entity 'SUSPECTED' named entity 'CULTURE'

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