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About:
Comparison of a home-based (multi) systemic intervention to promoting Medication AdheRence and Self-management among kidney transplant recipients with care-as-usual: the MARS randomized controlled trial protocol
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research paper
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Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Comparison of a home-based (multi) systemic intervention to promoting Medication AdheRence and Self-management among kidney transplant recipients with care-as-usual: the MARS randomized controlled trial protocol
Creator
Beck, Denise
Boonstra, Charlotte
Massey, Emma
Rechards, Marloes
Tielen, Mirjam
Timman, Reinier
Van Busschbach, Jan
Van De Wetering, Jacqueline
Van Gelder, Teun
Van Saase, Jan
Versteegh, Josette
Weimar, Willem
Zietse, Robert
Source
Medline; PMC
abstract
BACKGROUND: After kidney transplantation non-adherence and inadequate self-management undermine clinical outcomes and quality of life. Both have been demonstrated to be substantial in all age groups. However, interventions promoting adherence and self-management among kidney transplant recipients that have proven to be effective are scarce. In this study we aim to develop and test an intervention to optimize adherence and self-management. In this article we describe the background and design of the trial entitled ‘promoting Medication AdheRence and Self-management among kidney transplant recipients’ (MARS-trial)’. METHODS/DESIGN: This is a single-center, parallel arm randomized controlled trial. Nonadherent kidney transplant recipients aged 12 years or older are eligible for inclusion. Patients will be randomly assigned to either the experimental or a control group. The control group will receive care-as-usual. The experimental group will receive care-as-usual plus the MARS-intervention. The MARS-intervention is an outreaching intervention, based on the principles of (multi) systemic therapy which means involving the social network. A standardized intervention protocol is used for consistency but we will tailor the behavior change techniques used to the specific needs and determinants of each patient. The primary outcome of medication adherence will be measured using electronic monitoring. Secondary outcome measures regarding medication adherence and self-management are also assessed. Data is collected at baseline (T0), after a run-in period (T1), at six months post-baseline/end of treatment (T2) and after a six month follow-up period (T3). DISCUSSION: We combined elements of (multi) systemic therapy and evidence-based behavior change techniques to create an outreaching and highly individualized intervention. In this trial we will investigate the impact on medication adherence and self-management after kidney transplantation. TRIAL REGISTRATION: Netherlands Trial Register,trial number NTR7462. Registered 7th September 2018, https://www.trialregister.nl/trial/7264
has issue date
2020-08-28
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bibo:doi
10.1186/s12882-020-02008-z
bibo:pmid
32859157
has license
no-cc
sha1sum (hex)
b4c5c86273998495717fbf403d352d658622ce82
schema:url
https://doi.org/10.1186/s12882-020-02008-z
resource representing a document's title
Comparison of a home-based (multi) systemic intervention to promoting Medication AdheRence and Self-management among kidney transplant recipients with care-as-usual: the MARS randomized controlled trial protocol
has PubMed Central identifier
PMC7453377
has PubMed identifier
32859157
schema:publication
BMC Nephrol
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covid:b4c5c86273998495717fbf403d352d658622ce82#body_text
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schema:about
of
named entity 'age'
named entity 'effective'
named entity 'kidney transplant'
named entity 'protocol'
named entity 'OPTIMIZE'
named entity 'self-management'
named entity 'optimize'
named entity 'However'
named entity 'develop'
named entity 'adherence'
named entity 'Medication AdheRence'
named entity 'self-management'
named entity 'power analysis'
named entity 'internal consistency'
named entity 'medication adherence'
named entity 'health care professional'
named entity 'phase 3'
named entity 'Dutch language'
named entity 'SSS'
named entity 'Generalized Anxiety Disorder'
named entity 'immunosuppressive medication'
named entity 'nurse practitioner'
named entity 'RCT'
named entity 'MEMS'
named entity 'control group'
named entity 'non-adherence'
named entity 'control group'
named entity 'quality of life'
named entity 'kidney transplant'
named entity 'nephrologist'
named entity 'Basel'
named entity 'experimental group'
named entity 'self-management'
named entity 'Self-management'
named entity 'medication adherence'
named entity 'outpatient clinic'
named entity 'control group'
named entity 'electronic monitoring device'
named entity 'social network'
named entity 'Medication adherence'
named entity 'kidney transplant'
named entity 'control group'
named entity 'pediatric hospital'
named entity 'Dutch'
named entity 'nephrologist'
named entity 'kidney transplant'
named entity 'parallel-group'
named entity 'control group'
named entity 'social network'
named entity 'physical health'
named entity '31, 33'
named entity 'continuity correction'
named entity 'dependent variable'
named entity 'MEMS'
named entity 'non-adherence'
named entity 'regression analysis'
named entity 'PHQ-9'
named entity 'SSS'
named entity 'GAD-7'
named entity 'control group'
named entity 'treatment groups'
named entity 'PiH'
named entity 'Cronbach's alpha'
named entity 'self-management'
named entity 'study protocol'
named entity 'Dutch'
named entity 'confounding variable'
named entity 'self-management'
named entity 'Mental health'
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