About: instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder

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About: instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder
Creator	Avia, Komlan Baudry, Lyam Cock, J Coelho, Susana Cormier, Alexandre Godfroy, Olivier Guiglielmoni, Nadège Koszul, Romain Loe Mie, Yann Marie-Nelly, Hervé Sterck, Lieven Zimmer, Christophe
Source	PMC
abstract	Hi-C exploits contact frequencies between pairs of loci to bridge and order contigs during genome assembly, resulting in chromosome-level assemblies. Because few robust programs are available for this type of data, we developed instaGRAAL, a complete overhaul of the GRAAL program, which has adapted the latter to allow efficient assembly of large genomes. instaGRAAL features a number of improvements over GRAAL, including a modular correction approach that optionally integrates independent data. We validate the program using data for two brown algae, and human, to generate near-complete assemblies with minimal human intervention.
has issue date	2020-06-18(xsd:dateTime)
bibo:doi	10.1186/s13059-020-02041-z
bibo:pmid	32552806
has license	cc-by
sha1sum (hex)	b4fb01153b1766d6ab7fb70816cc61b3e14d8815
schema:url	https://doi.org/10.1186/s13059-020-02041-z
resource representing a document's title	instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder
has PubMed Central identifier	PMC7386250
has PubMed identifier	32552806
schema:publication	Genome Biol
resource representing a document's body	covid:b4fb01153b1766d6ab7fb70816cc61b3e14d8815#body_text
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