About: Dietary Phytochemicals Target Cancer Stem Cells for Cancer Chemoprevention

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Dietary Phytochemicals Target Cancer Stem Cells for Cancer Chemoprevention
Creator	Chan, M Fong, Dunne Chan, Marion Fong, D
Source	PMC
abstract	Cancer is a multistep process involving genetic and epigenetic changes in the somatic genome. Genetic mutations as well as environmental factors lead to the initiation, promotion, and progression of cancer. Cancer progression ends in tumor metastasis to distant sites, and metastasis is the major reason for cancer patient deaths. Recent experimental evidence suggests the pivotal role of cancer stem cells. A tumor is heterogeneous and composed of different cell types. The cancer stem cells in the tumor have the capacity both to self-renew and differentiate to sustain the tumor. Features of cancer stem cells are described in this review, with an emphasis on the role that dietary phytochemicals may play in cancer chemoprevention. Ingredients in the diet can inhibit cancer cells and cancer stem cells. These compounds include curcumin from curry, epigallocatechin gallate from green tea, resveratrol from red wine, genistein from soy, sulforaphane from broccoli, and many others. Current research findings advocate the beneficial effects towards cancer chemoprevention via uptake of a combination of different dietary phytochemicals.
has issue date	2013-12-10(xsd:dateTime)
bibo:doi	10.1007/978-1-4614-9326-6_5
has license	no-cc
sha1sum (hex)	b5ceb3f7fefb203914e45da4ed49051c920d5094
schema:url	https://doi.org/10.1007/978-1-4614-9326-6_5
resource representing a document's title	Dietary Phytochemicals Target Cancer Stem Cells for Cancer Chemoprevention
has PubMed Central identifier	PMC7122321
schema:publication	Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy
resource representing a document's body	covid:b5ceb3f7fefb203914e45da4ed49051c920d5094#body_text
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