About: Risk factors for disease progression in COVID-19 patients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Risk factors for disease progression in COVID-19 patients
Creator	Chang, Min Kim, Bong-Ok Park, Donghwi Park, Yu-Kyung
source	Medline; PMC
abstract	BACKGROUND: Coronavirus disease (COVID-19) is rapidly spreading worldwide. Although 10–20% of patients with COVID-19 have severe symptoms, little is known about the risk factors related to the aggravation of COVID-19 symptoms from asymptomatic or mild to severe disease states. METHODS: This retrospective study included 211 patients who were asymptomatic or with mild presentations of COVID-19. We evaluated the differences in demographic and clinical data between the cured (discharged to home) and transferred (aggravated to severe-stage COVID-19) groups. RESULTS: A multivariate logistic analysis showed that body temperature, chills, initial chest X-ray findings, and the presence of diabetes were significantly associated with predicting the progression to severe stage of COVID-19 (p < 0.05). The odds ratio of transfer in patients with COVID-19 increased by 12.7-fold for abnormal findings such as haziness or consolidation in initial chest X-ray, 6.32-fold for initial symptom of chills, and 64.1-fold for diabetes. CONCLUSIONS: Even if patients are asymptomatic or have mild symptoms, clinicians should closely observe patients with COVID-19 presenting with chills, body temperature > 37.5 °C, findings of pneumonia in chest X-ray, or diabetes.
has issue date	2020-06-23(xsd:dateTime)
bibo:doi	10.1186/s12879-020-05144-x
bibo:pmid	32576139
has license	cc-by
sha1sum (hex)	b5f6b5308b73b35eab499e9e3b345b0f89172db1
schema:url	https://doi.org/10.1186/s12879-020-05144-x
resource representing a document's title	Risk factors for disease progression in COVID-19 patients
has PubMed Central identifier	PMC7309210
has PubMed identifier	32576139
schema:publication	BMC Infect Dis
resource representing a document's body	covid:b5f6b5308b73b35eab499e9e3b345b0f89172db1#body_text
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