About: Role of Cellular Lipids in Positive-Sense RNA Virus Replication Complex Assembly and Function

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Role of Cellular Lipids in Positive-Sense RNA Virus Replication Complex Assembly and Function
Creator	Miller, David Stapleford, Kenneth
Source	Medline; PMC
abstract	Positive-sense RNA viruses are responsible for frequent and often devastating diseases in humans, animals, and plants. However, the development of effective vaccines and anti-viral therapies targeted towards these pathogens has been hindered by an incomplete understanding of the molecular mechanisms involved in viral replication. One common feature of all positive-sense RNA viruses is the manipulation of host intracellular membranes for the assembly of functional viral RNA replication complexes. This review will discuss the interplay between cellular membranes and positive-sense RNA virus replication, and will focus specifically on the potential structural and functional roles for cellular lipids in this process.
has issue date	2010-04-29(xsd:dateTime)
bibo:doi	10.3390/v2051055
bibo:pmid	21994671
has license	cc-by
sha1sum (hex)	b6fa578aa0397c1d6e2e0340b8581eb2c318974a
schema:url	https://doi.org/10.3390/v2051055
resource representing a document's title	Role of Cellular Lipids in Positive-Sense RNA Virus Replication Complex Assembly and Function
has PubMed Central identifier	PMC3187604
has PubMed identifier	21994671
schema:publication	Viruses
resource representing a document's body	covid:b6fa578aa0397c1d6e2e0340b8581eb2c318974a#body_text
is schema:about of	named entity 'VIRUS REPLICATION' named entity 'RNA' named entity 'cellular' named entity 'Replication' named entity 'ROLE' named entity 'POSITIVE' named entity 'FUNCTION' named entity 'FOCUS' named entity 'EFFECTIVE' named entity 'MANIPULATION' named entity 'VIRAL RNA' named entity 'ASSEMBLY' named entity 'INVOLVED' named entity 'VIRUS REPLICATION' named entity 'ANIMALS' named entity 'INCOMPLETE' named entity 'VACCINES' named entity 'RESPONSIBLE' named entity 'POSITIVE-SENSE RNA VIRUSES' named entity 'MECHANISMS' named entity 'ROLES' named entity 'DISCUSS' named entity 'PROCESS' named entity 'DISEASES' named entity 'HOST INTRACELLULAR' named entity 'RNA VIRUS' named entity 'REVIEW' named entity 'COMPLEXES' named entity 'PLANTS' named entity 'INTRACELLULAR MEMBRANES' named entity 'HUMANS' named entity 'SENSE' named entity 'VIRAL' named entity 'RNA REPLICATION' named entity 'ASSEMBLY' named entity 'COMPLEX' named entity 'RNA VIRUS' named entity 'CELLULAR' named entity 'LIPIDS' named entity 'PATHOGENS' named entity 'UNDERSTANDING' named entity 'STRUCTURAL' named entity 'THESE' named entity 'THERAPIES' named entity 'FREQUENT' named entity 'TARGETED' named entity 'POTENTIAL' named entity 'VIRAL REPLICATION' named entity 'MEMBRANES' named entity 'CELLULAR' named entity 'SENSE' named entity 'FEATURE' named entity 'LIPIDS' named entity 'POSITIVE' named entity 'DEVELOPMENT' named entity 'COMMON' named entity 'FUNCTIONAL' named entity 'MOLECULAR' named entity 'interplay' named entity 'assembly' named entity 'However' named entity 'This' named entity 'focus' named entity 'plants' named entity 'viral replication' named entity 'development' named entity 'anti-viral' named entity 'virus replication' named entity 'molecular mechanisms' named entity 'cellular membranes' named entity 'intracellular membranes' named entity 'lipids' named entity 'viral genome replication' named entity 'replicase' named entity 'complex function' named entity 'Brome mosaic virus' named entity 'viruses' named entity 'virus' named entity 'positive-sense RNA' named entity 'Positive-sense'

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