About: Early report on published outcomes in kidney transplant recipients compared to non-transplant patients infected with COVID-19

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About: Early report on published outcomes in kidney transplant recipients compared to non-transplant patients infected with COVID-19 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Early report on published outcomes in kidney transplant recipients compared to non-transplant patients infected with COVID-19
Creator	Aziz, Fahad Djamali, Arjang Garg, Neetika Mandelbrot, Didier Mohamed, Maha Parajuli, Sandesh Astor, Brad Singh, Tripti
Source	Elsevier; Medline; PMC
abstract	Abstract Background Kidney transplant recipients (KTR) present unique characteristics including disease vintage, immunosuppression, and single functioning kidneys. We conducted preliminary analyses to assess the impact of COVID-19 on outcomes in KTR compared to non-transplant patients. Methods We evaluated published information in peer-reviewed journals between 01/01/20 and 04/24/2020 with available data on AKI, renal replacement therapy (RRT), intensive care unit (ICU) stay, and death, and compared clinical outcomes in KTR versus non-transplant recipients with COVID-19. Results A total of 19 published articles were identified, including a total of 88 KTR and 5,342 non-transplant patients. The sample size varied between 2 and 2,634. Mean age was 58.6 years vs. 58.9 years in KTR vs. non-transplant. Patient-level incidence of AKI (27.5% vs. 13.3%, p<0.001), RRT (15.4% vs. 3.3%, p<0.001), ICU stay (34.1% vs. 15.1%, p<0.001), and death (22.7% vs 16.2%, p=0.10), was higher in KTR, representing relative risks of 2.06 (1.44, 2.96), 4.72 (2.62, 8.51), 2.25 (1.67, 3.03), and 1.41 (0.95, 2.08), respectively. Conclusion Early results suggest that the KTR are at significantly greater risk of AKI, RRT, and ICU stay from COVID-19 infection compared to the general population. The risk of death may not be significantly different.
has issue date	2020-07-13(xsd:dateTime)
bibo:doi	10.1016/j.transproceed.2020.07.002
bibo:pmid	32753243
has license	els-covid
sha1sum (hex)	ba5e24c495ac824892e352f8e7c9743502080fd3
schema:url	https://doi.org/10.1016/j.transproceed.2020.07.002
resource representing a document's title	Early report on published outcomes in kidney transplant recipients compared to non-transplant patients infected with COVID-19
has PubMed Central identifier	PMC7357494
has PubMed identifier	32753243
schema:publication	Transplant Proc
resource representing a document's body	covid:ba5e24c495ac824892e352f8e7c9743502080fd3#body_text
is schema:about of	named entity 'word count' named entity 'kidney transplant' named entity 'kidney transplant' named entity 'transplant' named entity '200' named entity 'COVID-19' named entity 'Word count' named entity 'COVID' named entity 'Wuhan' named entity 'T-cell depletion' named entity 'Acute Respiratory Distress Syndrome' named entity 'COVID' named entity 'clinical outcomes' named entity 'virus' named entity 'higher risk' named entity 'infection' named entity 'infection' named entity 'KTR' named entity 'KTR' named entity 'COVID' named entity 'selection bias' named entity 'Single case' named entity 'suppressed immune systems' named entity 'SARS' named entity 'KTRs' named entity 'COVID' named entity 'case series' named entity 'follow-up' named entity 'infection' named entity 'KTRs' named entity 'chronic kidney disease' named entity 'ICU' named entity 'dexamethasone' named entity 'intensive care unit' named entity 'transplant recipients' named entity 'KTR' named entity 'China' named entity 'COVID' named entity 'statistical difference' named entity 'KTR' named entity 'steroids' named entity 'COVID' named entity 'autopsies' named entity 'KTR' named entity 'acute kidney injury' named entity 'COVID' named entity 'SARS' named entity 'induction therapy' named entity 'SARS' named entity 'virus' named entity 'KTR' named entity 'general population' named entity 'case reports' named entity 'kidney transplantation' named entity 'COVID' named entity 'intravenous' named entity 'ICU' named entity 'RRT' named entity 'COVID-19 infection' named entity 'higher risk' named entity 'COVID-19 infection' named entity 'COVID' named entity 'kidney transplant' named entity 'COVID-19' named entity 'kidneys' named entity 'coronavirus' named entity 'infection' named entity 'KTR' named entity 'RRT' named entity 'ICU' named entity 'RRT' named entity 'p-value' named entity 'Columbia University, New York' named entity 'immunosuppression'

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