About: Duration of wheezy episodes in early childhood is independent of the microbial trigger

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About: Duration of wheezy episodes in early childhood is independent of the microbial trigger Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Duration of wheezy episodes in early childhood is independent of the microbial trigger
Creator	Bisgaard, Hans Bønnelykke, Klaus Johnston, Sebastian Sevelsted, Astrid Carlsson, Christian Vissing, Nadja Copenhagen,
Source	Elsevier; Medline; PMC
abstract	Background Wheezy episodes in young children are often triggered by viral and bacterial respiratory tract infections, but there is little evidence supporting the hypothesis that symptom duration depends on the specific microbial trigger. Objective We sought to investigate whether the duration of wheezy episodes in young children depends on the microbial trigger. Methods Two hundred eighty-three children from the Copenhagen Prospective Study on Asthma in Childhood2000 at-risk birth cohort were prospectively examined for common airway pathogenic bacteria and viruses during acute wheezy episodes in the first 3 years of life. Findings were related to symptomatic duration of episodes, as monitored in daily diary cards from birth. Results Eight hundred thirty-seven samples were investigated for viruses, bacteria, or both. Both viruses and bacteria were identified in 55% of episodes, bacteria were identified exclusively in 31% of episodes, and viruses were identified exclusively in 10% of episodes. The median duration of acute symptoms was 9 days (interquartile range, 5-16 days), and duration was independent of bacterial or viral species. Conclusions The duration of wheezy episodes was independent of pathogenic airway bacterial or viral species. This suggests that symptom burden from infections is dependent on other factors, such as environmental exposures or host factors. The common term viral wheeze seems inappropriate in view of the finding of pathogenic bacteria in 86% of wheezy episodes.
has issue date	2015-11-30(xsd:dateTime)
bibo:doi	10.1016/j.jaci.2015.05.003
bibo:pmid	26100088
has license	els-covid
sha1sum (hex)	ba7b8836962a0ac4f39544acba17a59d5c699371
schema:url	https://doi.org/10.1016/j.jaci.2015.05.003
resource representing a document's title	Duration of wheezy episodes in early childhood is independent of the microbial trigger
has PubMed Central identifier	PMC7172099
has PubMed identifier	26100088
schema:publication	Journal of Allergy and Clinical Immunology
resource representing a document's body	covid:ba7b8836962a0ac4f39544acba17a59d5c699371#body_text
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